Articles with "significance cancer" as a keyword



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Cancer as a tissue: The significance of cancer‐stromal interactions in the development, morphogenesis and progression of human upper digestive tract cancer

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Published in 2018 at "Pathology International"

DOI: 10.1111/pin.12674

Abstract: We review the significance of cancer‐stromal interactions (CSIs) in the development, morphogenesis and progression of human gastric and esophageal cancer based on the data obtained from co‐culture experiments. Orthotopic fibroblasts in the gastric cancer stroma… read more here.

Keywords: cancer stromal; stromal interactions; morphogenesis; cancer ... See more keywords
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Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer.

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.18311

Abstract: The membrane-bound molecules programmed death 1 (PD-1) and its ligand PD-L1 (PD-1/PD-L1) belong to the immune checkpoint pathway. PD-1 pathway downregulates effector T cells in immune response, thereby causing immune suppression. Recent studies have revealed… read more here.

Keywords: soluble predictive; prognostic significance; pathway; significance ... See more keywords