Use of Bayesian decision analysis to maximize value in patient-centered randomized clinical trials in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biopharmaceutical statistics"
DOI: 10.1080/10543406.2023.2170400
Abstract: A fixed one-sided significance level of 5% is commonly used to interpret the statistical significance of randomized clinical trial (RCT) outcomes. While it is necessary to reduce the false positive rate, the threshold used could… read more here.
Keywords: analysis; significance; value; significance level ... See more keywords
Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics
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DOI: 10.3390/jpm11010059
Abstract: An unaddressed and important issue is the role age plays in modulating response to short acting β2-agonists in individuals with asthma. The objective of this study was to identify whether age modifies genetic associations of… read more here.
Keywords: genome wide; response; age; single nucleotide ... See more keywords
Identification of Suitable Drug Combinations for Treating COVID-19 Using a Novel Machine Learning Approach: The RAIN Method
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DOI: 10.3390/life12091456
Abstract: Simple Summary This study follows an improved approach to systematic reviews, called the Systematic Review and Artificial Intelligence Network Meta-Analysis (RAIN), registered within PROSPERO (CRD42021256797), in which, the PRISMA criterion is still considered. Drugs used… read more here.
Keywords: level; covid; significance level; treatment ... See more keywords