Evolutionary dynamics and significance of multiple subclonal mutations in cancer.
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DOI: 10.1016/j.dnarep.2017.06.002
Abstract: For the last 40 years the authors have collaborated on trying to understand the complexities of human cancer by formulating testable mathematical models that are based on mutation accumulation in human malignancies. We summarize the… read more here.
Keywords: subclonal mutations; multiple subclonal; dynamics significance; cancer ... See more keywords