High liver stiffness values by transient elastography related to metabolic syndrome and harmful alcohol use in a large Spanish cohort
Sign Up to like & getrecommendations! Published in 2021 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12109
Abstract: Abstract Background and Aims Transient elastography (TE) to estimate liver stiffness has proved to be very useful in the diagnosis of chronic liver disease. Here, we intend to evaluate its use in a large Spanish… read more here.
Keywords: liver; metabolic syndrome; cacld; significant fibrosis ... See more keywords
Lifestyle and silymarin: a fight against liver damage in NAFLD associated - prediabetic disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes and Metabolic Disorders"
DOI: 10.1007/s40200-020-00576-3
Abstract: Background Nonalcoholic fatty liver disease (NAFLD) is common in both prediabetic patients and healthy overweight individuals, yet it remains understudied. This study investigates the effects of hepatic steatosis on fibrosis and evaluates the major predictors… read more here.
Keywords: silymarin; study; prediabetic patients; significant fibrosis ... See more keywords
Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18754-5
Abstract: Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 non-NAFLD controls are analyzed using 16S rRNA sequencing; an… read more here.
Keywords: fibrosis; obese subjects; gut microbiome; non obese ... See more keywords
Diagnostic performance of elastography on liver fibrosis in antiviral treatment-naive chronic hepatitis B patients: a meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology Report"
DOI: 10.1093/gastro/goac005
Abstract: Abstract Background This study aimed to assess the performance of transient elastography (TE), two-dimensional shear wave elastography (2D-SWE), and magnetic resonance elastography (MRE) for staging significant fibrosis and cirrhosis in untreated chronic hepatitis B (CHB)… read more here.
Keywords: fibrosis; significant fibrosis; swe mre; elastography ... See more keywords
Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein and type 4 collagen 7S: useful markers for the diagnosis of significant fibrosis in patients with non‐alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14156
Abstract: The fibrosis stage of liver is associated with the long‐term outcomes in patients with non‐alcoholic fatty liver disease (NAFLD). However, significant fibrosis, defined as fibrosis stages 2–4, is associated with an elevated risk of progression… read more here.
Keywords: liver disease; significant fibrosis; patients non; fibrosis ... See more keywords
Validation of magnetic resonance elastography plus fibrosis‐4 for significant fibrosis in nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15893
Abstract: MEFIB (the combination of magnetic resonance elastography [MRE] ≥ 3.3 kPa and fibrosis‐4 (FIB‐4) ≥ 1.6) is useful for detecting patients with significant fibrosis (fibrosis stage ≥ 2) having nonalcoholic fatty liver disease (NAFLD). However,… read more here.
Keywords: magnetic resonance; nonalcoholic fatty; fatty liver; resonance elastography ... See more keywords
Shear wave dispersion to assess liver disease progression in Fontan-associated liver disease
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271223
Abstract: Aim We aimed to analyze the dispersion slope (DS) using shear wave dispersion (SWD) in patients with Fontan-associated liver disease (FALD) and to investigate its utility as a biomarker of disease progression. Methods This cross-sectional… read more here.
Keywords: dispersion; disease; shear wave; significant fibrosis ... See more keywords
Acoustic radiation force impulse elastography and liver fibrosis risk scores in severe obesity.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of endocrinology and metabolism"
DOI: 10.20945/2359-3997000000397
Abstract: Objective Identifying significant fibrosis is crucial to evaluate the prognosis and therapeutic interventions in patients with nonalcoholic fatty liver disease (NAFLD). We assessed the performance of acoustic radiation force impulse (ARFI) elastography, APRI, FIB-4, Forns,… read more here.
Keywords: fibrosis; elastography; liver; significant fibrosis ... See more keywords
Significant fibrosis assessed by liver biopsy among Chinese bariatric surgery patients: A prospective cross-sectional study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1090598
Abstract: Background Fibrosis stages affect clinical prognoses related to nonalcoholic fatty liver disease (NAFLD). However, data on the prevalence and clinical features of significant fibrosis are scarce in Chinese bariatric surgery patients. We aimed to investigate… read more here.
Keywords: surgery patients; chinese bariatric; significant fibrosis; bariatric surgery ... See more keywords
The LAC Score Indicates Significant Fibrosis in Patients With Chronic Drug-Induced Liver Injury: A Large Biopsy-Based Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.734090
Abstract: Currently, there are no satisfactory noninvasive methods for the diagnosis of fibrosis in patients with chronic drug-induced liver injury (DILI). Our goal was to develop an algorithm to improve the diagnostic accuracy of significant fibrosis… read more here.
Keywords: fibrosis; study; cohort; patients chronic ... See more keywords
Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein as a Screening Tool for Significant Liver Fibrosis in Health Checkup
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22010040
Abstract: Chronic liver disease is generally widespread, and a test for screening fibrotic subjects in a large population is needed. The ability of Wisteria floribunda agglutinin-positive mac-2 binding protein (WFA+-M2BP) to detect significant fibrosis was investigated… read more here.
Keywords: fibrosis; liver fibrosis; health checkup; significant fibrosis ... See more keywords