High liver stiffness values by transient elastography related to metabolic syndrome and harmful alcohol use in a large Spanish cohort
Sign Up to like & getrecommendations! Published in 2021 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12109
Abstract: Abstract Background and Aims Transient elastography (TE) to estimate liver stiffness has proved to be very useful in the diagnosis of chronic liver disease. Here, we intend to evaluate its use in a large Spanish… read more here.
Keywords: liver; metabolic syndrome; cacld; significant fibrosis ... See more keywords
Lifestyle and silymarin: a fight against liver damage in NAFLD associated - prediabetic disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes and Metabolic Disorders"
DOI: 10.1007/s40200-020-00576-3
Abstract: Background Nonalcoholic fatty liver disease (NAFLD) is common in both prediabetic patients and healthy overweight individuals, yet it remains understudied. This study investigates the effects of hepatic steatosis on fibrosis and evaluates the major predictors… read more here.
Keywords: silymarin; study; prediabetic patients; significant fibrosis ... See more keywords
Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18754-5
Abstract: Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 non-NAFLD controls are analyzed using 16S rRNA sequencing; an… read more here.
Keywords: fibrosis; obese subjects; gut microbiome; non obese ... See more keywords
Early screening for chronic liver disease: impact of a FIB-4 first integrated care pathway to identify patients with significant fibrosis
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-66210-x
Abstract: Liver fibrosis is often undetected whereas it is the determinant of liver-related mortality. We evaluate a pathway based on the systematic calculation of FIB-4 to screen for advanced hepatic fibrosis. Systematic calculation of FIB-4 was… read more here.
Keywords: significant fibrosis; fib; care; liver ... See more keywords
Diagnostic performance of elastography on liver fibrosis in antiviral treatment-naive chronic hepatitis B patients: a meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology Report"
DOI: 10.1093/gastro/goac005
Abstract: Abstract Background This study aimed to assess the performance of transient elastography (TE), two-dimensional shear wave elastography (2D-SWE), and magnetic resonance elastography (MRE) for staging significant fibrosis and cirrhosis in untreated chronic hepatitis B (CHB)… read more here.
Keywords: fibrosis; significant fibrosis; swe mre; elastography ... See more keywords
Development and Validation of a Machine Learning-based Model for Prediction of Liver Fibrosis and MASH.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of clinical gastroenterology"
DOI: 10.1097/mcg.0000000000002166
Abstract: BACKGROUND AND AIM The development of accurate noninvasive tests to identify individuals with metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis is of great clinical importance. In this study, we aimed to develop 2 noninvasive diagnostic… read more here.
Keywords: fibrosis; significant fibrosis; machine learning; validation ... See more keywords
Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein and type 4 collagen 7S: useful markers for the diagnosis of significant fibrosis in patients with non‐alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14156
Abstract: The fibrosis stage of liver is associated with the long‐term outcomes in patients with non‐alcoholic fatty liver disease (NAFLD). However, significant fibrosis, defined as fibrosis stages 2–4, is associated with an elevated risk of progression… read more here.
Keywords: liver disease; significant fibrosis; patients non; fibrosis ... See more keywords
Validation of magnetic resonance elastography plus fibrosis‐4 for significant fibrosis in nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15893
Abstract: MEFIB (the combination of magnetic resonance elastography [MRE] ≥ 3.3 kPa and fibrosis‐4 (FIB‐4) ≥ 1.6) is useful for detecting patients with significant fibrosis (fibrosis stage ≥ 2) having nonalcoholic fatty liver disease (NAFLD). However,… read more here.
Keywords: magnetic resonance; nonalcoholic fatty; fatty liver; resonance elastography ... See more keywords
Reliability assessment of CT enhancement rate and extracellular volume in liver fibrosis prediction
Sign Up to like & getrecommendations! Published in 2025 at "BMC Gastroenterology"
DOI: 10.1186/s12876-025-03678-5
Abstract: Reliable, non-invasive evaluation of liver fibrosis is essential for early disease management. Computed tomography (CT)-based extracellular volume (ECV) fraction and portal venous phase enhancement rate (VP-ER) have shown potential in quantifying mild-to-moderate fibrosis. This study… read more here.
Keywords: enhancement rate; fibrosis; significant fibrosis; liver ... See more keywords
SAT-674 Predicting Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Patient Without Diabetes, Is FIB4 Still the Best?
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvaf149.109
Abstract: Abstract Disclosure: N.N. Nguyen-Jones: None. G. Arndt: None. M. Lindsay: None. S. Swartwood: None. S. Arrigain: None. R. Lopez Moscoso: None. A. Wieland: None. Introduction: With the rising prevalence of MASLD worldwide as well as… read more here.
Keywords: disease; fibrosis; none; study ... See more keywords
Shear wave dispersion to assess liver disease progression in Fontan-associated liver disease
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271223
Abstract: Aim We aimed to analyze the dispersion slope (DS) using shear wave dispersion (SWD) in patients with Fontan-associated liver disease (FALD) and to investigate its utility as a biomarker of disease progression. Methods This cross-sectional… read more here.
Keywords: dispersion; disease; shear wave; significant fibrosis ... See more keywords