Articles with "significant liver" as a keyword



Low 25 (OH) vitamin D levels are associated with increased prevalence of NAFLD and significant liver fibrosis.

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Published in 2023 at "Diabetes/metabolism research and reviews"

DOI: 10.1002/dmrr.3628

Abstract: AIMS Evidence on the role of 25-Hydroxyvitamin D (25(OH)D) in occurrence and progression of nonalcoholic fatty liver disease (NAFLD) is conflicting and population based-data are scarce. Here, we assess the association between 25(OH)D levels, NAFLD… read more here.

Keywords: liver fibrosis; prevalence nafld; vitamin; fibrosis ... See more keywords

Multiparametric ultrasomics of significant liver fibrosis: A machine learning-based analysis

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Published in 2018 at "European Radiology"

DOI: 10.1007/s00330-018-5680-z

Abstract: ObjectiveTo assess significant liver fibrosis by multiparametric ultrasomics data using machine learning.Materials and MethodsThis prospective study consisted of 144 patients with chronic hepatitis B. Ultrasomics—high-throughput quantitative data from ultrasound imaging of liver fibrosis—were generated using… read more here.

Keywords: machine; machine learning; fibrosis; liver fibrosis ... See more keywords
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Diagnosis of significant liver fibrosis in patients with chronic hepatitis B using a deep learning-based data integration network

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Published in 2022 at "Hepatology International"

DOI: 10.1007/s12072-021-10294-4

Abstract: Chronic hepatitis B virus (CHB) infection remains a major global health burden and the non-invasive and accurate diagnosis of significant liver fibrosis (≥ F2) in CHB patients is clinically very important. This study aimed to assess… read more here.

Keywords: diagnosis significant; chb patients; chronic hepatitis; deep learning ... See more keywords

A novel diagnostic algorithm to predict significant liver inflammation in chronic hepatitis B virus infection patients with detectable HBV DNA and persistently normal alanine transaminase

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-33412-z

Abstract: Significant liver inflammation might be found in 20–34% of chronic hepatitis B virus (HBV) infection patients with detectable HBV DNA and persistently normal alanine transaminase (ALT) (PNALT). We aimed to develop a diagnostic algorithm to… read more here.

Keywords: liver inflammation; significant liver; infection patients; patients detectable ... See more keywords

Multimorbidity and polypharmacy in diabetic patients with NAFLD

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Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000006761

Abstract: Abstract An observational study describing the number and type of chronic conditions and medications taken by diabetic patients with NAFLD and identifying characteristics that may impact liver disease severity or clinical management. Adults with type… read more here.

Keywords: disease; diabetic patients; significant liver; patients nafld ... See more keywords

A chitinase-3-like protein-1-based nomogram for identification of significant liver fibrosis in the general population

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Published in 2025 at "BMC Gastroenterology"

DOI: 10.1186/s12876-025-04277-0

Abstract: Serum chitinase-3-like protein-1 (CHI3L1) level is significantly correlated with fibrosis in chronic liver diseases. Therefore, we aimed to develop a CHI3L1-based model to predict significant liver fibrosis in the general population. This retrospective cross-sectional study… read more here.

Keywords: fibrosis; significant liver; population; model ... See more keywords

Explainable machine learning model for predicting the risk of significant liver fibrosis in patients with diabetic retinopathy

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Published in 2024 at "BMC Medical Informatics and Decision Making"

DOI: 10.1186/s12911-024-02749-z

Abstract: Diabetic retinopathy (DR), a prevalent complication in patients with type 2 diabetes, has attracted increasing attention. Recent studies have explored a plausible association between retinopathy and significant liver fibrosis. The aim of this investigation was… read more here.

Keywords: retinopathy; fibrosis; significant liver; fibrosis patients ... See more keywords

A prognostic model for development of significant liver fibrosis in HIV-hepatitis C co-infection

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0176282

Abstract: Background Liver fibrosis progresses rapidly in HIV-Hepatitis C virus (HCV) co-infected individuals partially due to heightened inflammation. Immune markers targeting stages of fibrogenesis could aid in prognosis of fibrosis. Methods A case-cohort study was nested… read more here.

Keywords: hiv hepatitis; fibrosis; liver fibrosis; model ... See more keywords

Association of High-Density Lipoprotein Cholesterol-Based Inflammatory Markers With MASLD and Significant Liver Fibrosis in US Adults: Insights From NHANES 2017–2020

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Published in 2025 at "Clinical and Translational Gastroenterology"

DOI: 10.14309/ctg.0000000000000873

Abstract: INTRODUCTION: Systemic inflammation and lipid metabolism disturbances are important hallmarks of the onset and progression of metabolic dysfunction-associated steatotic liver disease (MASLD). We aimed to explore the association of lymphocyte-high-density lipoprotein-cholesterol ratio (LHR), monocyte-HDL-C ratio… read more here.

Keywords: liver fibrosis; masld significant; significant liver; fibrosis ... See more keywords

Vibration-controlled transient elastography for significant fibrosis in treatment-naïve chronic hepatitis B patients: A systematic review and meta-analysis

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Published in 2024 at "Clinical and Molecular Hepatology"

DOI: 10.3350/cmh.2024.0371

Abstract: Background/Aims Accurate diagnosis of significant liver fibrosis in patients with chronic hepatitis B (CHB) is crucial when determining whether to initiate antiviral treatment (AVT). We conduct a meta-analysis to assess the diagnostic performance of vibration-controlled… read more here.

Keywords: liver fibrosis; meta analysis; significant liver; fibrosis ... See more keywords

Cumulative Betel Quid Chewing and the Risk of Significant Liver Fibrosis in Subjects With and Without Metabolic Syndrome

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Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.765206

Abstract: Background Betel quid chewing is associated with metabolic disorders, oral cancer, cardiovascular disease, and chronic liver diseases. Metabolic syndrome (MetS) is also a factor associated with liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). However, studies… read more here.

Keywords: liver fibrosis; fibrosis; betel quid; significant liver ... See more keywords