Articles with "sik inhibition" as a keyword



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Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0185426

Abstract: Osteoclasts are large multinucleated cells responsible for bone resorption. Excessive inflammatory activation of osteoclasts leads to bony erosions, which are the hallmark of several diseases such as rheumatoid arthritis (RA). Salt-inducible kinases (SIK) constitute a… read more here.

Keywords: sik inhibition; inhibition; salt inducible; inducible kinases ... See more keywords