Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages
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DOI: 10.1042/bcj20160646
Abstract: The salt-inducible kinases (SIKs) control a novel molecular switch regulating macrophage polarization. Pharmacological inhibition of the SIKs induces a macrophage phenotype characterized by the secretion of high levels of anti-inflammatory cytokines, including interleukin (IL)-10, and… read more here.
Keywords: anti inflammatory; inhibition sik2; differentiation; macrophage ... See more keywords