Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.806
Abstract: Sildenafil citrate is approved to treat erectile dysfunction. An orally disintegrating tablet (ODT) of sildenafil citrate that does not require swallowing or administration with fluids has been developed. The bioequivalence and bioavailability of sildenafil citrate… read more here.
Keywords: bioequivalence; healthy chinese; citrate; water ... See more keywords
Simultaneous Electrochemical Determination of Sildenafil Citrate and Tadalafil using a Multi Walled Carbon Nanotubes Modified Glassy Carbon Electrode by Adsorptive Stripping Linear Sweep Voltammetry
Sign Up to like & getrecommendations! Published in 2024 at "Electroanalysis"
DOI: 10.1002/elan.202400224
Abstract: An adsorptive stripping linear sweep voltammetric method was developed for the simultaneous determination of sildenafil citrate and tadalafil. The voltammetric working electrode was a glassy carbon electrode modified with carboxylic multi‐walled carbon nanotubes. The sensitivity… read more here.
Keywords: sildenafil citrate; citrate tadalafil; carbon;
Safety and efficacy of sildenafil citrate in treating erectile dysfunction in patients with combat-related post-traumatic stress disorder: A double-blind, randomized and placebo-controlled study
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.01.515
Abstract: To evaluate the safety and efficacy of sildenafil citrate for treating erectile dysfunction (ED) in patients with combat related post-traumatic stress disorder (PTSD). Patients and methods In all, 266 combat-exposed war veterans with ED (aged… read more here.
Keywords: safety efficacy; combat; sildenafil citrate; citrate treating ... See more keywords
Novel synthesis of nanocomposite for the extraction of Sildenafil Citrate (Viagra) from water and urine samples: Process screening and optimization.
Sign Up to like & getrecommendations! Published in 2017 at "Ultrasonics sonochemistry"
DOI: 10.1016/j.ultsonch.2017.03.045
Abstract: A sensitive analytical method is investigated to concentrate and determine trace level of Sildenafil Citrate (SLC) present in water and urine samples. The method is based on a sample treatment using dispersive solid-phase micro-extraction (DSPME)… read more here.
Keywords: extraction; water urine; sildenafil citrate; urine samples ... See more keywords
Tailoring of Bilosomal Nanogel for Augmenting the Off-Label Use of Sildenafil Citrate in Pediatric Pulmonary Hypertension
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DOI: 10.1021/acsomega.4c01133
Abstract: Pediatric pulmonary hypertension is a serious syndrome with significant morbidity and mortality. Sildenafil is widely used off-label in pediatric patients with pulmonary arterial hypertension. In this study, bile salt-stabilized nanovesicles (bilosomes) were screened for their… read more here.
Keywords: sildenafil citrate; pediatric pulmonary; sdf gel; pulmonary hypertension ... See more keywords
Serum l-carnitine and vitamin D levels may be low among oral sildenafil citrate non-responders
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Impotence Research"
DOI: 10.1038/s41443-018-0036-4
Abstract: This cross-sectional comparative study aimed to compare serum l-carnitine and 25(OH)D levels between men with ED non-responding for oral sildenafil citrate and healthy volunteers. Overall, 192 men, recruited from two University Hospitals, were allocated into… read more here.
Keywords: serum carnitine; oral sildenafil; sildenafil citrate;
Quality by design (QbD)-driven formulation of sildenafil citrate microparticles using quasi-emulsion technique for pulmonary delivery: an in vitro study
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2025.2525957
Abstract: Abstract Objective The goal of this research was to create inhalable microparticles to ensure the continuous delivery of sildenafil citrate (SC) to treat pulmonary arterial hypertension (PAH). This was done to address the limitations of… read more here.
Keywords: quality; sildenafil citrate; delivery; quality design ... See more keywords
Tartaric acid pellets as a core for extended release of sildenafil citrate: development via solid dispersion and factorial design
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DOI: 10.1080/03639045.2025.2571718
Abstract: Abstract Introduction Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by elevated pulmonary arterial pressure, causing vascular remodeling and eventual right heart failure. Sildenafil citrate (SC), a selective phosphodiesterase-5 inhibitor, used in PAH management;… read more here.
Keywords: sildenafil citrate; release; extended release; tartaric acid ... See more keywords
Development and characterization of polymer-coated liposomes for vaginal delivery of sildenafil citrate
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery"
DOI: 10.1080/10717544.2016.1247925
Abstract: Abstract Vaginal administration of sildenafil citrate has shown recently to develop efficiently the uterine lining with subsequent successful embryo implantation following in vitro fertilization. The aim of the present study was to develop sildenafil-loaded liposomes… read more here.
Keywords: permeation; delivery; sildenafil citrate; chitosan coated ... See more keywords
Enhanced dissolution of sildenafil citrate as dry foam tablets
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2017.1281952
Abstract: Abstract Dry foam formulation technology is alternative approach to enhance dissolution of the drug. Sildenafil citrate was suspended in sodium dodecyl sulfate solution and adding a mixture of maltodextrin and mannitol as diluent to form… read more here.
Keywords: dry foam; sildenafil citrate; dissolution; citrate ... See more keywords
Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes
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DOI: 10.1155/2019/8478750
Abstract: The aim of our study was to determine whether sildenafil citrate influences the production of Th1- (TNF-α, INF-γ) or Th2-type (TGF-β, IL-10) cytokines by lymphocytes of healthy men. Sildenafil citrate (SC) is a selective blocker… read more here.
Keywords: citrate influences; influences production; healthy men; sildenafil citrate ... See more keywords