piRNA-independent transposon silencing by the Drosophila THO complex.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.08.021
Abstract: piRNAs guide Piwi/Panoramix-dependent H3K9me3 chromatin modification and transposon silencing during Drosophila germline development. The THO RNA export complex is composed of Hpr1, Tho2, and Thoc5-7. Null thoc7 mutations, which displace Thoc5 and Thoc6 from a… read more here.
Keywords: independent transposon; transposon silencing; pirna independent; transposon ... See more keywords
Optogenetic Neuronal Silencing in Drosophila during Visual Processing
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DOI: 10.1038/s41598-017-14076-7
Abstract: Optogenetic channels and ion pumps have become indispensable tools in neuroscience to manipulate neuronal activity and thus to establish synaptic connectivity and behavioral causality. Inhibitory channels are particularly advantageous to explore signal processing in neural… read more here.
Keywords: processing; visual processing; optogenetic neuronal; neuronal silencing ... See more keywords
Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddx051
Abstract: SOX5 encodes a transcription factor that is expressed in multiple tissues including heart, lung and brain. Mutations in SOX5 have been previously found in patients with amyotrophic lateral sclerosis (ALS) and developmental delay, intellectual disability… read more here.
Keywords: sox5 leads; drosophila ortholog; sox5; ortholog sox5 ... See more keywords
Induction of transposon silencing in the Drosophila germline
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297917050042
Abstract: In this review we consider the role of the piRNA system in transposable element silencing in the Drosophila melanogaster germline. We focus on new data that demonstrate the mechanisms of initiation of piRNA biogenesis in… read more here.
Keywords: silencing drosophila; drosophila germline; transposon silencing; induction transposon ... See more keywords