Articles with "silencing function" as a keyword



Anti-silencing function 1B promotes the progression of pancreatic cancer by activating c-Myc

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Published in 2022 at "International Journal of Oncology"

DOI: 10.3892/ijo.2022.5456

Abstract: The present study aimed to explore the role of histone chaperone anti-silencing function 1B (ASF1B) in pancreatic cancer and the underlying mechanism. The biological function of ASF1B was investigated in pancreatic cancer cell lines (PANC-1… read more here.

Keywords: silencing function; anti silencing; pancreatic cancer; activating myc ... See more keywords

Anti-silencing function 1B knockdown suppresses the malignant phenotype of colorectal cancer by inactivating the phosphatidylinositol 3-kinase/AKT pathway

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Published in 2022 at "World Journal of Gastrointestinal Oncology"

DOI: 10.4251/wjgo.v14.i12.2353

Abstract: BACKGROUND Mounting studies have highlighted the pivotal influence of anti-silencing function 1B (ASF1B) on the malignancy of cancers. AIM To explore the influence and mechanism of ASF1B in colorectal cancer (CRC). METHODS Quantitative real-time polymerase… read more here.

Keywords: silencing function; anti silencing; phosphatidylinositol kinase; crc ... See more keywords

Carcinogenic Role and Clinical Significance of Histone H3-H4 Chaperone Anti-silencing Function 1 B (ASF1B) in Lung Adenocarcinoma

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Published in 2024 at "Journal of Cancer"

DOI: 10.7150/jca.88777

Abstract: Histone H3-H4 chaperone anti-silencing function 1 (ASF1) plays an important role in the polymerization, transport, and modification of histones. However, the significance of ASF1B in lung adenocarcinoma (LUAD) is largely overlooked. We investigated the aberrant… read more here.

Keywords: lung; histone chaperone; asf1b; chaperone anti ... See more keywords