Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages.
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DOI: 10.1002/jbt.22994
Abstract: Atherosclerosis (AS) is a chronic inflammatory disease with the formation and accumulation of macrophage-derived foam cells in the subendothelial space of blood vessels as one major characteristic. Insulin-like growth factor 2 messenger RNA (mRNA) binding… read more here.
Keywords: expression; accumulation; silencing igf2bp1; lipid accumulation ... See more keywords