Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies.
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DOI: 10.1053/j.gastro.2022.08.040
Abstract: BACKGROUND AND AIMS Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury including steatohepatitis/NASH. However, the evidence supporting these claims has been controversial. A comprehensive, fundamental understanding… read more here.
Keywords: necroptosis; silencing ripk3; mlkl; pathology ... See more keywords