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   Articles with "silico analyses" as a keyword



In silico analyses of acetylcholinesterase (AChE) and its genetic variants in interaction with the anti‐Alzheimer drug Rivastigmine

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recommendations! Published in 2022 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.30277

Abstract: Alzheimer's disease (AD) is the leading cause of dementia worldwide. Despite causing great social and economic impact, there is currently no cure for AD. The most effective therapy to manage AD symptoms is based on… read more here.

Keywords: analyses acetylcholinesterase; interaction; ache; silico analyses ... See more keywords

Characterization of Lysinibacillus fusiformis strain S4C11: In vitro, in planta, and in silico analyses reveal a plant-beneficial microbe.

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recommendations! Published in 2020 at "Microbiological research"

DOI: 10.1016/j.micres.2020.126665

Abstract: Despite sharing many of the traits that have allowed the genus Bacillus to gain recognition for its agricultural relevance, the genus Lysinibacillus is not as well-known and studied. The present study employs in vitro, in… read more here.

Keywords: strain s4c11; lysinibacillus fusiformis; planta silico; silico analyses ... See more keywords

In silico analyses and global transcriptional profiling reveal novel putative targets for Pea3 transcription factor related to its function in neurons

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0170585

Abstract: Pea3 transcription factor belongs to the PEA3 subfamily within the ETS domain transcription factor superfamily, and has been largely studied in relation to its role in breast cancer metastasis. Nonetheless, Pea3 plays a role not… read more here.

Keywords: transcription; targets pea3; transcription factor; pea3 transcription ... See more keywords

Comprehensive in silico analyses of flavonoids elucidating the drug properties against kidney disease by targeting AIM2

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recommendations! Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0285965

Abstract: Kidney disorders are among the most common diseases and there is a scarcity of effective treatments for chronic kidney disease. There has been a progressive improvement in specific flavonoids for protective effects against kidney diseases.… read more here.

Keywords: drug; silico analyses; targeting aim2; kidney disease ... See more keywords

Exploring bacterial key genes and therapeutic agents for breast cancer among the Ghanaian female population: Insights from In Silico analyses

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recommendations! Published in 2024 at "PLOS ONE"

DOI: 10.1371/journal.pone.0312493

Abstract: Breast cancer (BC) is yet a significant global health challenge across various populations including Ghana, though several studies on host-genome associated with BC have been investigated molecular mechanisms of BC development and progression, and candidate… read more here.

Keywords: bacterial key; breast cancer; silico analyses; key genes ... See more keywords

A Novel Mutation (Lys31Arg) in the DMD Gene Impacts on Neuromuscular Dysfunctions found by Whole Exome Sequencing and In Silico Analyses in an Iranian Family.

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recommendations! Published in 2024 at "Current aging science"

DOI: 10.2174/0118746098280408240112112414

Abstract: BACKGROUND Duchene Muscular Disorder (DMD) is a severe X-linked recessive neuromuscular disease. Previous reports predicted that one-third of cases with a fatal X-linked recessive disease will be caused by a novel mutation, and the mutation… read more here.

Keywords: dmd; dmd gene; silico analyses; mutation ... See more keywords

Synergistic Effects of Novel Xanthone Derivatives and Mild Hyperthermia in Ovarian Cancer: Insights from Gene Expression and In Silico Analyses

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recommendations! Published in 2025 at "Cancers"

DOI: 10.3390/cancers17172896

Abstract: Simple Summary Ovarian cancer treatments often focus on novel derivatives of existing substances. This study examines xanthone derivatives combined with mild hyperthermia on TOV-21G and SK-OV-3 ovarian cancer cell lines. We analyzed the expression of… read more here.

Keywords: xanthone derivatives; ovarian cancer; silico analyses; expression ... See more keywords