Articles with "silico approach" as a keyword



An in‐silico approach exploring sorghum source:sink balance across sorghum hybrids: How many leaves are enough?

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Published in 2025 at "Crop Science"

DOI: 10.1002/csc2.21449

Abstract: Previous literature documented an imbalance for sorghum [Sorghum bicolor (L.) Moench] between source (leaves) and sink (grains), favoring the source. Therefore, reducing leaf number, anticipating maturity, and placing the dry‐down with more favorable environment might… read more here.

Keywords: silico approach; yield; sorghum hybrids; source ... See more keywords

In silico approach to quantify nucleus self-deformation on micropillared substrates

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Published in 2019 at "Biomechanics and Modeling in Mechanobiology"

DOI: 10.1007/s10237-019-01144-2

Abstract: Considering the major role of confined cell migration in biological processes and diseases, such as embryogenesis or metastatic cancer, it has become increasingly important to design relevant experimental set-ups for in vitro studies. Microfluidic devices… read more here.

Keywords: deformation micropillared; self deformation; deformation; nucleus self ... See more keywords

Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2☆

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Published in 2021 at "Egyptian Journal of Petroleum"

DOI: 10.1016/j.ejpe.2021.02.005

Abstract: World Health Organization declared COVID-19 as a global pandemic. A diverse array of drugs failed to combat. There is an immense need for novel lead molecules. Medicinal plants are the reservoir of secondary metabolites. In… read more here.

Keywords: magical bullets; approach; sars cov; tinospora cordifolia ... See more keywords

Evaluation of in silico approach for prediction of presence of opioid peptides in wheat

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Published in 2018 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2017.12.022

Abstract: Abstract Opioid like morphine and codeine are used for the management of pain, but are associated with serious side-effects limiting their use. Wheat gluten proteins were assessed for the presence of opioid peptides on the… read more here.

Keywords: silico approach; presence opioid; opioid peptides; opioid ... See more keywords

An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase

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Published in 2020 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2020.1828170

Abstract: Abstract Alzheimer's disease (AD) is a progressive neurological disorder affecting an estimated 10 million people worldwide. There is no cure for AD, and only a handful of drugs are known to provide some relief of… read more here.

Keywords: identify potential; disease; silico approach; medicinal plants ... See more keywords

The interaction of DNMT1 and DNMT3A epigenetic enzymes with phthalates and perfluoroalkyl substances: an in silico approach

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Published in 2022 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2021.2023642

Abstract: Abstract The occurrence of long-lasting adverse effects of the environmental contaminants on human health is a current emerging issue. In particular, phthalates, poly- and perfluoroalkyl substances are proposed to trigger toxic effects as well as… read more here.

Keywords: perfluoroalkyl substances; class; silico approach; interaction dnmt1 ... See more keywords

Application of an in silico approach identifies a genetic locus within ITGB2, and its interactions with HSPG2 and FGF9, to be associated with anterior cruciate ligament rupture risk.

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Published in 2023 at "European journal of sport science"

DOI: 10.1080/17461391.2023.2171906

Abstract: We developed a Biomedical Knowledge Graph model that is phenotype and biological function-aware through integrating knowledge from multiple domains in a Neo4j, graph database. All known human genes were assessed through the model to identify… read more here.

Keywords: interactions hspg2; cruciate ligament; silico approach; risk ... See more keywords
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Structural and Functional Elucidation of IF-3 Protein of Chloroflexus aurantiacus Involved in Protein Biosynthesis: An In Silico Approach

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Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/9050026

Abstract: Chloroflexus aurantiacus is a thermophilic bacterium that produces a multitude of proteins within its genome. Bioinformatics strategies can facilitate comprehending this organism through functional and structural interpretation assessments. This study is aimed at allocating the… read more here.

Keywords: protein; chloroflexus aurantiacus; protein biosynthesis; silico approach ... See more keywords

An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene

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Published in 2023 at "International Journal of Genomics"

DOI: 10.1155/2023/9705159

Abstract: Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms… read more here.

Keywords: structure; approach towards; silico approach; met gene ... See more keywords

Abstract 4194: An in-silico approach to identify genes required for polyamine transport

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-4194

Abstract: The purpose of this study was to use an in-silico approach to identify genes required for polyamine transport. Polyamines are small positively charged molecules that control vital cellular processes including cell proliferation and growth. Cells… read more here.

Keywords: polyamine transport; silico approach; transport; required polyamine ... See more keywords

A multi-epitope vaccine targeting a key virulence factor ClfA: An In-silico approach to combat Staphylococcus aureus infections

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Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0334885

Abstract: Staphylococcus aureus, a gram-positive opportunistic pathogen, presents a growing global threat due to the rise of multidrug-resistant (MDR) strains. To counter this, we designed a multi-epitope vaccine (MEV) targeting the ClfA virulence protein using an… read more here.

Keywords: silico approach; multi epitope; silico; staphylococcus aureus ... See more keywords