In silico approach to quantify nucleus self-deformation on micropillared substrates
Sign Up to like & getrecommendations! Published in 2019 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-019-01144-2
Abstract: Considering the major role of confined cell migration in biological processes and diseases, such as embryogenesis or metastatic cancer, it has become increasingly important to design relevant experimental set-ups for in vitro studies. Microfluidic devices… read more here.
Keywords: deformation micropillared; self deformation; deformation; nucleus self ... See more keywords
Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2☆
Sign Up to like & getrecommendations! Published in 2021 at "Egyptian Journal of Petroleum"
DOI: 10.1016/j.ejpe.2021.02.005
Abstract: World Health Organization declared COVID-19 as a global pandemic. A diverse array of drugs failed to combat. There is an immense need for novel lead molecules. Medicinal plants are the reservoir of secondary metabolites. In… read more here.
Keywords: magical bullets; approach; sars cov; tinospora cordifolia ... See more keywords
Evaluation of in silico approach for prediction of presence of opioid peptides in wheat
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.12.022
Abstract: Abstract Opioid like morphine and codeine are used for the management of pain, but are associated with serious side-effects limiting their use. Wheat gluten proteins were assessed for the presence of opioid peptides on the… read more here.
Keywords: silico approach; presence opioid; opioid peptides; opioid ... See more keywords
An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1828170
Abstract: Abstract Alzheimer's disease (AD) is a progressive neurological disorder affecting an estimated 10 million people worldwide. There is no cure for AD, and only a handful of drugs are known to provide some relief of… read more here.
Keywords: identify potential; disease; silico approach; medicinal plants ... See more keywords
The interaction of DNMT1 and DNMT3A epigenetic enzymes with phthalates and perfluoroalkyl substances: an in silico approach
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2021.2023642
Abstract: Abstract The occurrence of long-lasting adverse effects of the environmental contaminants on human health is a current emerging issue. In particular, phthalates, poly- and perfluoroalkyl substances are proposed to trigger toxic effects as well as… read more here.
Keywords: perfluoroalkyl substances; class; silico approach; interaction dnmt1 ... See more keywords
Application of an in silico approach identifies a genetic locus within ITGB2, and its interactions with HSPG2 and FGF9, to be associated with anterior cruciate ligament rupture risk.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of sport science"
DOI: 10.1080/17461391.2023.2171906
Abstract: We developed a Biomedical Knowledge Graph model that is phenotype and biological function-aware through integrating knowledge from multiple domains in a Neo4j, graph database. All known human genes were assessed through the model to identify… read more here.
Keywords: interactions hspg2; cruciate ligament; silico approach; risk ... See more keywords
Structural and Functional Elucidation of IF-3 Protein of Chloroflexus aurantiacus Involved in Protein Biosynthesis: An In Silico Approach
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/9050026
Abstract: Chloroflexus aurantiacus is a thermophilic bacterium that produces a multitude of proteins within its genome. Bioinformatics strategies can facilitate comprehending this organism through functional and structural interpretation assessments. This study is aimed at allocating the… read more here.
Keywords: protein; chloroflexus aurantiacus; protein biosynthesis; silico approach ... See more keywords
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Genomics"
DOI: 10.1155/2023/9705159
Abstract: Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms… read more here.
Keywords: structure; approach towards; silico approach; met gene ... See more keywords
An In-Silico Approach to Identify Therapeutic Target and Markers Associated with Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2022 at "Current diabetes reviews"
DOI: 10.2174/1573399819666220610191935
Abstract: BACKGROUND Renal disease in T2DM could arise independent of hyperglycemia, aka non diabetic kidney disease. Their prevalence ranges from 33%to72.5% among T2DM patients. Specific molecular signatures that distinguish Diabetic Nephropathy from NDKD (FSGS) in T2DM… read more here.
Keywords: approach identify; identify therapeutic; silico approach; analysis ... See more keywords
An in-silico Approach for Recognition of Long non-coding RNA-Associated Competing Endogenous RNA Axes in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Urology journal"
DOI: 10.22037/uj.v20i.7650
Abstract: Prostate cancer is among the most central sources of cancer-related mortalities. In order to find novel candidates for therapeutic strategies in this kind of cancer, we developed an in-silico method for identification of competing endogenous… read more here.
Keywords: prostate cancer; rna; silico approach; competing endogenous ... See more keywords
Methyltransferase as Antibiotics Against Foodborne Pathogens: An In Silico Approach for Exploring Enzyme as Enzymobiotics
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.800587
Abstract: The development of resistance in microbes against antibiotics and limited choice for the use of chemical preservatives in food lead the urgent need to search for an alternative to antibiotics. The enzymes are catalytic proteins… read more here.
Keywords: methyltransferase antibiotics; silico approach; antibiotics foodborne; pathogens silico ... See more keywords