Modeling an in silico platform to predict chromatographic profiles of UV filters using ChromSimulator
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105002
Abstract: Abstract The use of Analytical Quality by Design (AQbD) concepts is increasing for rational development of analytical methods of liquid chromatography. To facilitate the use of the AQbD approach, we developed an in silico tool… read more here.
Keywords: modeling silico; predict chromatographic; silico platform; platform ... See more keywords
A novel in silico platform for a fully automatic personalized brain tumor growth.
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2019.12.012
Abstract: Glioblastoma Multiforme is the most common and most aggressive type of brain tumors grade four astrocytoma. Although accurate prediction of Glioblastoma borders and shape is absolutely essential for neurosurgeons, there are not many in silico… read more here.
Keywords: novel silico; platform fully; silico platform; brain ... See more keywords
compuGUT: An in silico platform for simulating intestinal fermentation
Sign Up to like & getrecommendations! Published in 2017 at "SoftwareX"
DOI: 10.1016/j.softx.2017.06.004
Abstract: Abstract The microbiota inhabiting the colon and its effect on health is a topic of significant interest. In this paper, we describe the compuGUT — a simulation tool developed to assist in exploring interactions between… read more here.
Keywords: simulating intestinal; platform simulating; silico platform; compugut silico ... See more keywords
Development of an In Silico Platform (TRIPinRNA) for the Identification of Novel RNA Intramolecular Triple Helices and Their Validation Using Biophysical Techniques.
Sign Up to like & getrecommendations! Published in 2024 at "Biochemistry"
DOI: 10.1021/acs.biochem.4c00334
Abstract: There are surprisingly few RNA intramolecular triple helices known in the human transcriptome. The structure has been most well-studied as a stability-element at the 3' end of lncRNAs such as MALAT1 and NEAT1, but the… read more here.
Keywords: intramolecular triple; triple helices; human transcriptome; silico platform ... See more keywords
In-silico platform for the multifunctional design of 3D printed conductive components
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56707-y
Abstract: The effective electric resistivity of conductive thermoplastics manufactured by filament extrusion methods is determined by both the material constituents and the printing parameters. The former determines the multifunctional nature of the composite, whereas the latter… read more here.
Keywords: conductive components; multifunctional design; platform multifunctional; printed conductive ... See more keywords
DARTpaths, an in silico platform to investigate molecular mechanisms of compounds
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac767
Abstract: Abstract Summary Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate… read more here.
Keywords: silico platform; dartpaths silico; molecular mechanisms; platform investigate ... See more keywords
Locuaz: an in silico platform for protein binders optimization
Sign Up to like & getrecommendations! Published in 2024 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btae492
Abstract: Abstract Motivation Engineering high-affinity binders targeting specific antigenic determinants remains a challenging and often daunting task, requiring extensive experimental screening. Computational methods have the potential to accelerate this process, reducing costs and time, but only… read more here.
Keywords: locuaz silico; protein binders; silico platform; mutation ... See more keywords