The rate and role of pseudogenes of the Mycobacterium tuberculosis complex
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000876
Abstract: Whole-genome sequence analyses have significantly contributed to the understanding of virulence and evolution of the Mycobacterium tuberculosis complex (MTBC), the causative pathogens of tuberculosis. Most MTBC evolutionary studies are focused on single nucleotide polymorphisms and… read more here.
Keywords: mycobacterium tuberculosis; predicted pseudogenes; tuberculosis; silico predicted ... See more keywords
DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1166546
Abstract: The global SARS-CoV-2 pandemic caused significant social and economic disruption worldwide, despite highly effective vaccines being developed at an unprecedented speed. Because the first licensed vaccines target only single B-cell antigens, antigenic drift could lead… read more here.
Keywords: cell; k18 hace2; silico predicted; cell epitopes ... See more keywords
In Silico Predicted Antifungal Peptides: In Vitro and In Vivo Anti-Candida Activity
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fungi"
DOI: 10.3390/jof7060439
Abstract: It has been previously demonstrated that synthetic antibody-derived peptides could exert a significant activity in vitro, ex vivo, and/or in vivo against microorganisms and viruses, as well as immunomodulatory effects through the activation of immune… read more here.
Keywords: activity silico; vitro vivo; parent peptide; predicted antifungal ... See more keywords