In vitro antiproliferative activity of glabridin derivatives and their in silico target identification
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DOI: 10.1080/14786419.2018.1530228
Abstract: Abstract Novel Mannich base derivatives of glabridin were synthesized and their antiproliferative activity were performed along with our previously reported glabridin-chalcone hybrids molecules (GCHMs) against various human cell lines MDA-MB-231 (breast adenocarcinoma), HEK-293 (embryonic kidney… read more here.
Keywords: silico target; activity glabridin; glabridin derivatives; antiproliferative activity ... See more keywords
Antiproliferative and Carbonic Anhydrase II Inhibitory Potential of Chemical Constituents from Lycium shawii and Aloe vera: Evidence from In Silico Target Fishing and In Vitro Testing
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DOI: 10.3390/ph13050094
Abstract: Lycium shawii Roem. & Schult and resin of Aloe vera (L.) BURM. F. are commonly used in Omani traditional medication against various ailments. Herein, their antiproliferative and antioxidant potential was explored. Bioassay-guided fractionation of the… read more here.
Keywords: carbonic anhydrase; lycium shawii; vera; silico target ... See more keywords