N‐Silylation of Amines Mediated by Et 3 SiH/KO t Bu
Sign Up to like & getrecommendations! Published in 2019 at "Helvetica Chimica Acta"
DOI: 10.1002/hlca.201900235
Abstract: Silylation of primary and secondary amines is reported, using triethylsilane as the silylating reagent in the presence of potassium tert-butoxide (KOtBu). The reaction proceeds well in the presence of 0.2 equiv of KOtBu. In competition… read more here.
Keywords: silylation amines; silylation; mediated sih; amines mediated ... See more keywords
Sequential protocol for C(sp)–H carboxylation with CO2: KOtBu-catalyzed C(sp)–H silylation and KOtBu-mediated carboxylation
Sign Up to like & getrecommendations! Published in 2018 at "Science China Chemistry"
DOI: 10.1007/s11426-017-9163-2
Abstract: CO2 incorporation into C–H bonds is an important and interesting topic. Herein a sequential protocol for C(sp)–H carboxylation by employing a metal-free C–H activation/catalytic silylation reaction in conjunction with KOtBu-mediated carboxylation with CO2 was established,… read more here.
Keywords: silylation; kotbu; co2; protocol carboxylation ... See more keywords
Zinc-Catalyzed Dehydrogenative Silylation of Indoles
Sign Up to like & getrecommendations! Published in 2017 at "Organometallics"
DOI: 10.1021/acs.organomet.7b00382
Abstract: A unique Lewis acid/base system consisting of zinc triflate and pyridine was found to act as an effective catalyst for making an N(indolyl)–Si bond in a dehydrogenative fashion. Execution in a nitrile medium brings out… read more here.
Keywords: silylation; system; catalyzed dehydrogenative; dehydrogenative silylation ... See more keywords
Organoelectrophotocatalytic C-H Silylation of Heteroarenes.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00144
Abstract: An organoelectrophotocatalytic approach for the C-H silylation of heteroarenes through dehydrogenation cross-coupling with H2 evolution has been developed. The organoelectrophotocatalytic strategy is carried out under a simple and efficient monocatalytic system by employing 9,10-phenanthrenequinone both… read more here.
Keywords: organoelectrophotocatalytic silylation; silylation heteroarenes; silylation;
Free-Radical-Promoted Site-Selective C-H Silylation of Arenes by Using Hydrosilanes.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02717
Abstract: A free-radical-promoted aryl/heteroaryl C-H silylation using hydrosilane was developed. This cross-dehydrogenative silylation enables both electron-rich and electron-poor aromatics to afford the desired arylsilanes in unique selectivity. A "para-selectivity" was observed by examination of over 54… read more here.
Keywords: silylation; selective silylation; site selective; free radical ... See more keywords
Ruthenium(II) Acetate Catalyzed Synthesis of Silylated Oxazoles via C-H Silylation and Dehalogenation.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00085
Abstract: An efficient ruthenium(II)-catalyzed intermolecular selective ortho C-H silylation of 2-aryloxazoles has been described for the first time, which provides a convenient and practical pathway for the synthesis of versatile organosilane compounds with good functional group… read more here.
Keywords: silylation; dehalogenation; acetate catalyzed; ruthenium acetate ... See more keywords
Catalytic Net Oxidative C-C Activation and Silylation of Cyclopropanols with a Traceless Acetal Directing Group.
Sign Up to like & getrecommendations! Published in 2022 at "ACS catalysis"
DOI: 10.1021/acscatal.1c04628
Abstract: Redox-neutral carbon-carbon (C-C) bond activation and functionalization strategies of cyclopropanols that give metallo homoenolate have offered merits to construct a range of useful β-functionalized ketones in an inverse-polarity fashion. Discovery and identification of oxidative C-C… read more here.
Keywords: net oxidative; silylation; oxidative activation; acetal directing ... See more keywords
Switchable C–H Silylation of Indoles Catalyzed by a Thermally Induced Frustrated Lewis Pair
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b01847
Abstract: It is a challenging task to achieve regioselective C–H silylation of indoles with Ph2SiH2, as bis(indol-3-yl)-substituted silanes are always obtained along with the C3-silylated indoles. Without adding any additive, we developed an Al(C6F5)3-based catalyst system… read more here.
Keywords: silylation; induced frustrated; lewis pair; thermally induced ... See more keywords
Kinetic Analysis and Sequencing of Si-H and C-H Bond Activation Reactions: Direct Silylation of Arenes Catalyzed by an Iridium-Polyhydride.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c07578
Abstract: The saturated trihydride IrH3{κ3-P,O,P-[xant(PiPr2)2]} (1; xant(PiPr2)2 = 9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene) coordinates the Si-H bond of triethylsilane, 1,1,1,3,5,5,5-heptamethyltrisiloxane, and triphenylsilane to give the σ-complexes IrH3(η2-H-SiR3){κ2-cis-P,P-[xant(PiPr2)2]}, which evolve to the dihydride-silyl derivatives IrH2(SiR3){κ3-P,O,P-[xant(PiPr2)2]} (SiR3 = SiEt3 (2), SiMe(OSiMe3)2 (3),… read more here.
Keywords: direct silylation; silylation; bond; silylation arenes ... See more keywords
A Combined Computational and Experimental Study of Rh-Catalyzed C-H Silylation with Silacyclobutanes: Insights Leading to a More Efficient Catalyst System.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c13335
Abstract: The study of new C-H silylation reagents and reactions remains an important topic. We reported that under Rh catalysis, silacyclobutanes (SCBs) for the first time were able to react with C(sp2)-H and C(sp3)-H bonds, however… read more here.
Keywords: silylation; experimental study; efficient catalyst; combined computational ... See more keywords
Enantioselective synthesis of acyclic monohydrosilanes by steric hindrance assisted C-H silylation.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02307e
Abstract: Herein, a rhodium-catalyzed desymmetrization of dihydrosilanes with heterocyclic compounds via intermolecular dehydrogenative C-H silylation is developed. The strategy tolerates a variety of thianaphthene and thiophene derivatives, giving rise to a wide range of silicon-stereogenic acyclic… read more here.
Keywords: silylation; enantioselective synthesis; monohydrosilanes steric; synthesis acyclic ... See more keywords