Copper-Catalyzed Defluorinative Borylation and Silylation of gem-Difluoroallyl Groups.
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DOI: 10.1021/acs.orglett.0c02321
Abstract: Stereodefined (Z)-fluoroalkenes are bioisosteres of amides and synthetic precursors to value-added fluorinated compounds, but their stereoselective synthesis remains challenging. Herein, we report a copper-catalyzed formal SN2' defluorinative borylation of 3-substituted 3,3-difluoropropenes to form 3-fluoroallylboronic esters… read more here.
Keywords: borylation silylation; catalyzed defluorinative; silylation gem; defluorinative borylation ... See more keywords