Cardioprotective effect of silymarin nanoemulsion on 5-fluorouracil-induced cardiotoxicity in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200060
Abstract: 5-Fluorouracil (5-FU)-associated cardiotoxicity has been ranked as the second most common cause of cardiotoxicity induced by chemotherapeutic drugs after anthracyclines. In the present study, we investigated the protective impacts of silymarin (SIL) and silymarin nanoemulsion… read more here.
Keywords: fluorouracil; silymarin nanoemulsion; sil sln; cardiotoxicity ... See more keywords
Quality by design based silymarin nanoemulsion for enhancement of oral bioavailability
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2017.05.019
Abstract: Abstract Silymarin has been approved as a safe herbal hepatoprotective drug as well as drug of choice for several hepatic disorders. However it suffers from the problem of poor oral bioavailability. In current work silymarin… read more here.
Keywords: silymarin nanoemulsion; oral bioavailability; quality design; drug ... See more keywords