Single-Molecule Array (Simoa) Technology as a Highly Sensitive Screening Tool for Protein-Protein Interactions.
Sign Up to like & getrecommendations! Published in 2025 at "ACS sensors"
DOI: 10.1021/acssensors.5c02047
Abstract: Transcription factor (TF) interactions are generally considered to be weak and transient, which enables the dynamic assembly and disassembly of transcription complexes. While advantageous for modulating cellular physiology, requiring rapid adaptation, these characteristics make it… read more here.
Keywords: transcription factor; simoa; protein; transcription ... See more keywords
Plasma p-tau217 in Alzheimer’s disease: Lumipulse and ALZpath SIMOA head-to-head comparison
Sign Up to like & getrecommendations! Published in 2024 at "Brain"
DOI: 10.1093/brain/awae368
Abstract: Abstract Plasma phosphorylated-tau217 (p-tau217) has been shown to be one of the most accurate diagnostic markers for Alzheimer’s disease. No studies have compared the clinical performance of p-tau217 as assessed by the fully automated Lumipulse… read more here.
Keywords: alzheimer disease; simoa; alzpath; tau217 ... See more keywords