ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism
Sign Up to like & getrecommendations! Published in 2017 at "ACS Omega"
DOI: 10.1021/acsomega.7b01054
Abstract: Although aldehyde oxidase (AO) is an important hepatic drug-metabolizing enzyme, it remains understudied and is consequently often overlooked in preclinical studies, an oversight that has resulted in the failure of multiple clinical trials. AO’s preclusion… read more here.
Keywords: ecoao simple; system; metabolism; drug ... See more keywords
A simple D–π–A system of phenanthroimidazole-π-fluorenone for highly efficient non-doped bipolar AIE luminogens: synthesis, and molecular optical, thermal and electrochemical properties
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/c9nj05226g
Abstract: A series of hybrid organic bipolar fluorescent aggregation-induced emission (AIE) luminogens have been synthesized with D–π–A architecture using phenanthroimidazole as a conjugate by incorporating a fluorenone moiety at the C2 position of a rigid skeleton… read more here.
Keywords: system phenanthroimidazole; aie luminogens; simple system; fluorenone ... See more keywords