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Published in 2024 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23769
Abstract: Neonatal infection with herpes simplex virus (HSV) is associated with significant morbidity, high mortality, and long‐term neurological sequelae. We report the clinical case of an infant with HSV encephalitis, where the initial diagnosis was established…
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Keywords:
simplex encephalitis;
cranial ultrasound;
herpes simplex;
ultrasound neonatal ... See more keywords
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Published in 2022 at "Neurology and Therapy"
DOI: 10.1007/s40120-022-00330-2
Abstract: Introduction In spite of antiviral treatment, herpes simplex encephalitis (HSE) remains associated with a poor prognosis and often results in neurological impairment. The B cell response in HSE is poorly understood. The objective of this…
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Keywords:
herpes simplex;
time;
cell;
simplex encephalitis ... See more keywords
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Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.11.002
Abstract: ABSTRACT Pritelivir, a helicase‐primase inhibitor, has excellent in vitro and in vivo activity against human herpes simplex virus (HSV). Mice lethally infected with HSV type 1 or 2, including acyclovir‐resistant strains, were treated 72 h…
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Keywords:
pritelivir;
hsv;
treatment;
simplex encephalitis ... See more keywords
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Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e03667
Abstract: Purpose Although it is a well-known disease, the occurrence of Herpes simplex encephalitis (HSE) during a hospital stay may render the diagnosis particularly challenging. The objective of this report is to alert clinicians about the…
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Keywords:
new type;
infection;
simplex encephalitis;
type icu ... See more keywords
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Published in 2020 at "IDCases"
DOI: 10.1016/j.idcr.2020.e00884
Abstract: Herpes Simplex Virus (HSV) continues to be an important pathogen inflicting encephalitis in adults and children globally that entails high morbidity and mortality. Prompt diagnosis and treatment are the keys to minimize potential sequelae of…
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Keywords:
manifestation;
case herpes;
simplex encephalitis;
herpes simplex ... See more keywords
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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-48287-0
Abstract: Encephalitis is a rare and potentially fatal manifestation of herpes simplex type 1 infection. Following genome-wide genetic analyses, we identified a previously uncharacterized and very rare heterozygous variant in the E3 ubiquitin ligase WWP2, in…
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Keywords:
simplex encephalitis;
encephalitis;
herpes simplex;
ubiquitin ligase ... See more keywords
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Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-59042-4
Abstract: Herpes simplex encephalitis (HSE) caused by HSV-1 is the most common non-epidemic viral encephalitis, and the neuropathogenesis of HSE remains elusive. This work describes a 3D human neurovascular unit (NVU) model that allows to explore…
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Keywords:
simplex encephalitis;
encephalitis;
neurovascular unit;
herpes simplex ... See more keywords
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Published in 2020 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2020.1849551
Abstract: Herpes Simplex Virus (HSV) is the commonest cause of fatal sporadic encephalitis, with HSV-1causing most of the cases and HSV-2 usually presenting in immunocompromised patients. 1 Herpes simplex en...
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Keywords:
following successful;
simplex encephalitis;
encephalitis;
herpes simplex ... See more keywords
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Published in 2021 at "Archives of Clinical Neuropsychology"
DOI: 10.1093/arclin/acab062.96
Abstract: Herpes simplex encephalitis (HSE) is a rare neurological condition (~2–4 per million) marked by brain inflammation caused by herpes simplex virus (HSV). HSE is associated with both cognitive and neuropsychiatric symptoms, particularly memory and executive…
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Keywords:
neuropsychiatric symptoms;
case;
simplex encephalitis;
herpes simplex ... See more keywords
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Published in 2023 at "Annals of Medicine and Surgery"
DOI: 10.1097/ms9.0000000000000462
Abstract: Introduction: Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection.…
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Keywords:
infection;
hsv;
abusing morphine;
case ... See more keywords
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Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2019-230005
Abstract: A 75-year-old woman presented with new onset of confusion, intense episodic dizziness and formed visual hallucinations. Herpes simplex encephalitis and non-convulsive temporal lobe seizures were confirmed with cerebrospinal fluid (CSF) and electroencephalography testing. In addition,…
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Keywords:
simplex encephalitis;
encephalitis;
severe presentation;
herpes simplex ... See more keywords