Articles with "simplex encephalitis" as a keyword



Cranial ultrasound in neonatal herpes simplex encephalitis

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Published in 2024 at "Journal of Clinical Ultrasound"

DOI: 10.1002/jcu.23769

Abstract: Neonatal infection with herpes simplex virus (HSV) is associated with significant morbidity, high mortality, and long‐term neurological sequelae. We report the clinical case of an infant with HSV encephalitis, where the initial diagnosis was established… read more here.

Keywords: simplex encephalitis; cranial ultrasound; herpes simplex; ultrasound neonatal ... See more keywords

Intrathecally Expanding B Cell Clones in Herpes Simplex Encephalitis: A Case Report

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Published in 2022 at "Neurology and Therapy"

DOI: 10.1007/s40120-022-00330-2

Abstract: Introduction In spite of antiviral treatment, herpes simplex encephalitis (HSE) remains associated with a poor prognosis and often results in neurological impairment. The B cell response in HSE is poorly understood. The objective of this… read more here.

Keywords: herpes simplex; time; cell; simplex encephalitis ... See more keywords

Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis

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Published in 2018 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2017.11.002

Abstract: ABSTRACT Pritelivir, a helicase‐primase inhibitor, has excellent in vitro and in vivo activity against human herpes simplex virus (HSV). Mice lethally infected with HSV type 1 or 2, including acyclovir‐resistant strains, were treated 72 h… read more here.

Keywords: pritelivir; hsv; treatment; simplex encephalitis ... See more keywords
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Herpes simplex encephalitis: A new type of “ICU-acquired infection”?

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Published in 2020 at "Heliyon"

DOI: 10.1016/j.heliyon.2020.e03667

Abstract: Purpose Although it is a well-known disease, the occurrence of Herpes simplex encephalitis (HSE) during a hospital stay may render the diagnosis particularly challenging. The objective of this report is to alert clinicians about the… read more here.

Keywords: new type; infection; simplex encephalitis; type icu ... See more keywords

A case of herpes simplex 2 encephalitis with an unusual radiographic manifestation

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Published in 2020 at "IDCases"

DOI: 10.1016/j.idcr.2020.e00884

Abstract: Herpes Simplex Virus (HSV) continues to be an important pathogen inflicting encephalitis in adults and children globally that entails high morbidity and mortality. Prompt diagnosis and treatment are the keys to minimize potential sequelae of… read more here.

Keywords: manifestation; case herpes; simplex encephalitis; herpes simplex ... See more keywords

Herpes simplex encephalitis due to a mutation in an E3 ubiquitin ligase

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-48287-0

Abstract: Encephalitis is a rare and potentially fatal manifestation of herpes simplex type 1 infection. Following genome-wide genetic analyses, we identified a previously uncharacterized and very rare heterozygous variant in the E3 ubiquitin ligase WWP2, in… read more here.

Keywords: simplex encephalitis; encephalitis; herpes simplex; ubiquitin ligase ... See more keywords

A microengineered 3D human neurovascular unit model to probe the neuropathogenesis of herpes simplex encephalitis

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-59042-4

Abstract: Herpes simplex encephalitis (HSE) caused by HSV-1 is the most common non-epidemic viral encephalitis, and the neuropathogenesis of HSE remains elusive. This work describes a 3D human neurovascular unit (NVU) model that allows to explore… read more here.

Keywords: simplex encephalitis; encephalitis; neurovascular unit; herpes simplex ... See more keywords
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Herpes simplex encephalitis following successful coiling of aneurysmal subarachnoid haemorrhage.

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Published in 2020 at "British journal of neurosurgery"

DOI: 10.1080/02688697.2020.1849551

Abstract: Herpes Simplex Virus (HSV) is the commonest cause of fatal sporadic encephalitis, with HSV-1causing most of the cases and HSV-2 usually presenting in immunocompromised patients. 1 Herpes simplex en... read more here.

Keywords: following successful; simplex encephalitis; encephalitis; herpes simplex ... See more keywords

A-78 Interdisciplinary Consultation in a Case of Herpes Simplex Encephalitis with Unique Neuropsychiatric Symptoms

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Published in 2021 at "Archives of Clinical Neuropsychology"

DOI: 10.1093/arclin/acab062.96

Abstract: Herpes simplex encephalitis (HSE) is a rare neurological condition (~2–4 per million) marked by brain inflammation caused by herpes simplex virus (HSV). HSE is associated with both cognitive and neuropsychiatric symptoms, particularly memory and executive… read more here.

Keywords: neuropsychiatric symptoms; case; simplex encephalitis; herpes simplex ... See more keywords

Herpes simplex encephalitis in a patient abusing morphine: a case report from Nepal

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Published in 2023 at "Annals of Medicine and Surgery"

DOI: 10.1097/ms9.0000000000000462

Abstract: Introduction: Herpes simplex encephalitis results from either primary infection with the herpes simplex virus (HSV) or reactivation of latent HSV residing within the nuclei of sensory neurons. Opioid’s administration is known to reactivate HSV infection.… read more here.

Keywords: infection; hsv; abusing morphine; case ... See more keywords

Severe presentation of antibody-negative, postinfectious steroid-responsive encephalitis and atonic bladder after herpes simplex encephalitis

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Published in 2019 at "BMJ Case Reports"

DOI: 10.1136/bcr-2019-230005

Abstract: A 75-year-old woman presented with new onset of confusion, intense episodic dizziness and formed visual hallucinations. Herpes simplex encephalitis and non-convulsive temporal lobe seizures were confirmed with cerebrospinal fluid (CSF) and electroencephalography testing. In addition,… read more here.

Keywords: simplex encephalitis; encephalitis; severe presentation; herpes simplex ... See more keywords