Herpes-A Not So Simple(x) History.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2017.2879
Abstract: Centuries ago, the term herpes referred to a group of blistering diseases. The origin of the word is derived from the ancient Greek herpein, meaning “to creep” or “move slowly,” characterizing the latent onset of… read more here.
Keywords: cold sores; herpes simple; simple history; herpes simplex ... See more keywords
Monosynaptic restriction of the anterograde herpes simplex virus strain H129 for neural circuit tracing
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25451
Abstract: Identification of synaptic partners is a fundamental task for systems neuroscience. To date, few reliable techniques exist for whole brain labeling of downstream synaptic partners in a cell‐type‐dependent and monosynaptic manner. Herein, we describe a… read more here.
Keywords: strain h129; simplex virus; virus strain; anterograde herpes ... See more keywords
Pharmacokinetics and Safety Study of HN0037, a Novel Anti‐Human Herpes Simplex Virus Inhibitor, in Healthy Volunteers
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1138
Abstract: HN0037 is a helicase‐primase inhibitor developed to treat herpes simplex virus (HSV) infection. This study evaluated the safety, tolerability, and pharmacokinetics of HN0037, following oral administration in healthy volunteers. This double‐blind, placebo‐controlled, phase 1 study… read more here.
Keywords: healthy volunteers; simplex virus; inhibitor; study ... See more keywords
Nonclinical safety evaluation of two vaccine candidates for herpes simplex virus type 2 to support combined administration in humans
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4404
Abstract: Herpes simplex virus type 2 (HSV‐2) is the most common cause of genital disease worldwide. The development of an effective HSV‐2 vaccine would significantly impact global health based on the psychological distress caused by genital… read more here.
Keywords: simplex virus; nonclinical safety; virus type; two vaccine ... See more keywords
Monkeypox virus, herpes simplex virus, and cytomegalovirus skin coinfections
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28500
Abstract: We read with interest the recent article entitled "Concomitant diagnosis of sexually transmitted infections and human monkeypox in patients attending a sexual health clinic in Milan, Italy" by Rizzo et al This article is protected… read more here.
Keywords: virus herpes; simplex virus; monkeypox virus; virus ... See more keywords
Conformational Change in Herpes Simplex Virus Entry Glycoproteins Detected by Dot Blot.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_18
Abstract: Conformational changes in viral membrane proteins drive membrane fusion, a critical step in virus entry and infection. Here we describe a simple and rapid virus blotting immunoassay to define conformational changes with a panel of… read more here.
Keywords: dot blot; virus entry; herpes simplex; simplex virus ... See more keywords
Multifluorescence Live Analysis of Herpes Simplex Virus Type-1 Replication.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_22
Abstract: The possibility to label specific viral and cellular structures with live cell markers such as autofluorescent proteins has greatly contributed to our understanding of diverse steps of the virus life cycle, as it allows for… read more here.
Keywords: virus type; live analysis; herpes simplex; simplex virus ... See more keywords
The Use of Microfluidic Neuronal Devices to Study the Anterograde Axonal Transport of Herpes Simplex Virus-1.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_25
Abstract: Understanding how herpes simplex virus-1 (HSV-1) interacts with different parts of the neuron is fundamental in understanding the mechanisms behind HSV-1 transport during primary and recurrent infections. In this chapter, we describe a unique neuronal… read more here.
Keywords: use microfluidic; microfluidic neuronal; transport; herpes simplex ... See more keywords
Herpes Simplex Virus Growth, Preparation, and Assay.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_3
Abstract: The human herpesvirus family members, in particular herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2), are abundant and extremely contagious viruses with a high seroprevalence in the human population emphasizing… read more here.
Keywords: virus growth; growth preparation; biology; herpes simplex ... See more keywords
Preparation of Herpes Simplex Virus Type 1 (HSV-1)-Based Amplicon Vectors.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9814-2_5
Abstract: Amplicon vectors, or amplicons, are defective, helper-dependent, herpes simplex virus type 1 (HSV-1)-based vectors. The main interest of amplicons as gene transfer tools stems from the fact that the genomes of these vectors do not… read more here.
Keywords: type hsv; virus type; herpes simplex; simplex virus ... See more keywords
Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2938-1
Abstract: Herpes simplex virus type-1 (HSV-1) is a ubiquitous pathogen that infects a large majority of the human population worldwide. It is also a leading cause of infection-related blindness in the developed world. HSV-1 infection of… read more here.
Keywords: infection; infection cornea; hsv infection; herpes simplex ... See more keywords