Formation and properties of amorphous magnesium-calcium phosphate particles in a simulated intestinal fluid.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2019.03.060
Abstract: HYPOTHESIS The endogenous self-assembly of amorphous magnesium-calcium phosphate (AMCP) nanoparticles in human small intestine is an intriguing and newly-discovered process involved in immune-surveillance mechanisms. The study of nano and microparticles formation in complex media mimicking… read more here.
Keywords: magnesium calcium; calcium phosphate; formation; intestinal fluid ... See more keywords
Topography of Simulated Intestinal Equilibrium Solubility
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b01238
Abstract: Oral administration of a solid dosage form requires drug dissolution in the gastrointestinal tract before absorption. Solubility is a key factor controlling dissolution, and it is recognized that, within the intestinal tract, this is influenced… read more here.
Keywords: topography; solubility; simulated intestinal; equilibrium solubility ... See more keywords
In Vitro Biopharmaceutical Equivalence of 5-mg Glibenclamide Tabletsin Simulated Intestinal Fluid Without Enzymes
Sign Up to like & getrecommendations! Published in 2021 at "Dissolution Technologies"
DOI: 10.14227/dt280121pgc2
Abstract: This research evaluated the biopharmaceutical equivalence in vitro of three brands of glibenclamide 5-mg tablets (reference, brand name, and generic drugs) from Lima, Peru following the guidelines of the Biopharmaceutical Classification System (BCS). Glibenclamide is… read more here.
Keywords: biopharmaceutical equivalence; simulated intestinal; drug; fluid without ... See more keywords
Dynamics of the Lipidome in a Colon Simulator
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo13030355
Abstract: Current evidence suggests that gut microbiome derived lipids play crucial role in the regulation of host lipid metabolism. However, not much is known about the dynamics of gut microbial lipids within the distinct gut biogeographic.… read more here.
Keywords: simulated intestinal; colon simulator; intestinal chyme; colon ... See more keywords