Advances in microgravity directed tissue engineering.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202768
Abstract: Tissue engineering aims to generate functional biological substitutes to repair, sustain, improve, or replace tissue function affected by disease. With the rapid development of space science, the application of simulated microgravity has become an active… read more here.
Keywords: microgravity; tissue engineering; simulated microgravity; advances microgravity ... See more keywords
Inhibition of Cell Cycle Progression, Induction of Apoptosis, and Changes in Surface Markers of MEG-01 Megakaryoblastic Cells Exposed to a Random Positioning Machine
Sign Up to like & getrecommendations! Published in 2019 at "Microgravity Science and Technology"
DOI: 10.1007/s12217-019-09737-3
Abstract: One cause of thrombocytopenia in astronauts after spaceflight is decreased platelet production. To increase our understanding of thrombopoiesis in humans while in space, we investigated the effects of simulated microgravity, achieved using a random positioning… read more here.
Keywords: random positioning; simulated microgravity; cell cycle; cell ... See more keywords
Change of growth promotion and disease resistant of wheat seedling by application of biocontrol bacterium Pseudochrobactrum kiredjianiae A4 under simulated microgravity
Sign Up to like & getrecommendations! Published in 2017 at "Acta Astronautica"
DOI: 10.1016/j.actaastro.2017.06.022
Abstract: Abstract Plant disease control and prevention in microgravity are critical for space plant cultivation. This study investigated the effects of a biocontrol bacterium Pseudochrobactrum kiredjianiae A4 on growth development and antifungal potential of wheat seedlings… read more here.
Keywords: plant; wheat; simulated microgravity; disease ... See more keywords
Osthole ameliorates simulated microgravity-induced bone loss through down-regulation of miR-34c-5p
Sign Up to like & getrecommendations! Published in 2021 at "Acta Astronautica"
DOI: 10.1016/j.actaastro.2021.03.015
Abstract: Abstract Bone loss severely threatens the heath of astronauts in long-term spaceflight and the effects of the developed countermeasures are limited. Emerging studies have revealed the positive role of osthole (OST) in induction of osteogenic… read more here.
Keywords: expression; bone loss; simulated microgravity; mir 34c ... See more keywords
Temporal changes in the markers of ribosome biogenesis in rat soleus muscle under simulated microgravity
Sign Up to like & getrecommendations! Published in 2021 at "Acta Astronautica"
DOI: 10.1016/j.actaastro.2021.05.036
Abstract: Abstract Skeletal muscle inactivity due to real or simulated microgravity results in a significant atrophy of muscle fibers. One of the key causes of disuse atrophy is a decrease in the rate of muscle protein… read more here.
Keywords: muscle; temporal changes; ribosome biogenesis; simulated microgravity ... See more keywords
Activation of HIF-1α and its downstream targets in rat hippocampus after long-term simulated microgravity exposure.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.078
Abstract: Microgravity has many detrimental impact on brain functions, however the underlying mechanism remain unclear. In present study, 28 days of tail-suspension (30°) was used to simulate microgravity in rats. We showed that oxidative stress in… read more here.
Keywords: hif; downstream targets; microgravity exposure; simulated microgravity ... See more keywords
Possibility of culturing the early developing kidney cells by utilizing simulated microgravity environment.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.08.012
Abstract: In recent years, the successful construction of tissues derived from established iPSCs has been disclosed, but it has been reported that the constructed tissues encounter problems of internal necrosis when their size increases. To solve… read more here.
Keywords: kidney cells; developing kidney; simulated microgravity; culture ... See more keywords
Simulated microgravity accelerates aging of human skeletal muscle myoblasts at the single cell level.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.09.037
Abstract: Earth's gravity is essential for maintaining skeletal muscle mass and function in the body. The role of gravity in the myogenic mechanism has been studied with animal experiments in the International Space Station. Recently, gravity-control… read more here.
Keywords: skeletal muscle; muscle; simulated microgravity; aging human ... See more keywords
Simulated Microgravity Conditions Modulate Ca2+ Transport through TRPV4 Channels
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1371
Abstract: Astronauts in space tend to lose ten times as much bone mass each month as severe osteoporosis patients on Earth. Multiple reports on unloading-induced osteoporosis in bed-ridden patients indicate that bone mass correlates positively with… read more here.
Keywords: microgravity conditions; simulated microgravity; trpv4 channels; ca2 ... See more keywords
Influence of gap height and flow field on global stoichiometry and heat losses during opposed flow flame spread over thin fuels in simulated microgravity
Sign Up to like & getrecommendations! Published in 2018 at "Combustion and Flame"
DOI: 10.1016/j.combustflame.2018.02.023
Abstract: Abstract This study characterizes thin fuel opposed flow flame spread in simulated microgravity for a range of gap heights and airflow velocities in a Narrow Channel Apparatus (NCA). One objective was to estimate gap heights… read more here.
Keywords: gap; flame; simulated microgravity; flame spread ... See more keywords
Effects of simulated microgravity on gene expression and biological phenotypes of a single generation Caenorhabditis elegans cultured on 2 different media.
Sign Up to like & getrecommendations! Published in 2017 at "Life sciences in space research"
DOI: 10.1016/j.lssr.2017.06.002
Abstract: Studies of multigenerational Caenorhabditis elegans exposed to long-term spaceflight have revealed expression changes of genes involved in longevity, DNA repair, and locomotion. However, results from spaceflight experiments are difficult to reproduce as space missions are… read more here.
Keywords: expression biological; simulated microgravity; gene expression; expression ... See more keywords