Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness/ADMET studies
Sign Up to like & getrecommendations! Published in 2021 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2021.12.018
Abstract: In view of the potential of traditional plant-based remedies (or phytomedicines) in the management of COVID-19, the present investigation was aimed at finding novel anti-SARS-CoV-2 molecules by in silico screening of bioactive phytochemicals (database) using… read more here.
Keywords: drug likeness; sars cov; likeness admet; anti sars ... See more keywords
Molecular Dynamics Simulation of Drug Solubilization Behavior in Surfactant and Cosolvent Injections
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DOI: 10.3390/pharmaceutics14112366
Abstract: Surfactants and cosolvents are often combined to solubilize insoluble drugs in commercially available intravenous formulations to achieve better solubilization. In this study, six marketed parenteral formulations with surfactants and cosolvents were investigated on the aggregation… read more here.
Keywords: simulation drug; solubilization; molecular dynamics; cosolvent ... See more keywords