Novel ligand-based docking; molecular dynamic simulations; and absorption, distribution, metabolism, and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimer's disease
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DOI: 10.1016/j.jpha.2017.07.006
Abstract: Acetylcholinesterase (AChE) plays an important role in Alzheimer's disease (AD). The excessive activity of AChE causes various neuronal problems, particularly dementia and neuronal cell deaths. Generally, anti-AChE drugs induce some serious neuronal side effects in… read more here.
Keywords: simulations absorption; alzheimer disease; dynamic simulations; docking molecular ... See more keywords