Molecular dynamics simulations of early steps in RNA‐mediated conversion of prions
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DOI: 10.1002/pro.3178
Abstract: The rate‐limiting step in prion diseases is the initial transition of a prion protein from its native form into a mis‐folded state in which the protein not only forms cell‐toxic aggregates but also becomes infectious.… read more here.
Keywords: rna mediated; molecular dynamics; simulations early; polyadenosine rna ... See more keywords