Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
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DOI: 10.1021/acs.molpharmaceut.0c00588
Abstract: Efficient delivery of oral drugs is dependent on their solubility in human intestinal fluid, a complex and dynamic fluid that contains colloidal structures composed of small molecules. These structures solubilize poorly water-soluble compounds, increasing their… read more here.
Keywords: intestinal fluids; molecular dynamics; fluid; interindividual variability ... See more keywords