Simultaneous delivery of anti-miRNA and docetaxel with supramolecular self-assembled “chitosome” for improving chemosensitivity of triple negative breast cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-020-00779-4
Abstract: At present, treating of triple negative breast cancer (TNBC) mainly depends on chemotherapy with more toxic side effects, but the effect is limited and it is highly prone to drug resistance. Gene therapy using anti-microRNAs… read more here.
Keywords: negative breast; delivery; simultaneous delivery; self assembled ... See more keywords
Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00256
Abstract: The derivative of protease inhibitor ritonavir (5-methyl-4-oxohexanoic acid ritonavir ester; RD) was recently recognized as a potent P-gp inhibitor and cancerostatic drug inhibiting the proteasome and STAT3 signaling. Therefore, we designed high-molecular-weight HPMA copolymer conjugates… read more here.
Keywords: star; dox; star dox; simultaneous delivery ... See more keywords
Preparation and characterization of a hydroxypropyl methylcellulose based wafer for simultaneous delivery of phenytoin and insulin as wound dressing material
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2049606
Abstract: Abstract In this study, a novel wafer based on Hydroxypropyl methylcellulose (HPMC) was prepared as a wound dressing for the simultaneous delivery of phenytoin (PT) and insulin; evaluation of the cutaneous wound repair property was… read more here.
Keywords: delivery phenytoin; wafer; simultaneous delivery; insulin ... See more keywords
Effects of Surfactants on Zein Cast Films for Simultaneous Delivery of Two Hydrophilic Active Components
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DOI: 10.3390/ma15082795
Abstract: In order to prepare edible films with outstanding antimicrobials and antioxidants utilized in applications of food and pharmaceutics, in this study, effects of surfactants on zein cast films for simultaneous delivery of lysozyme (LY) and… read more here.
Keywords: films simultaneous; cast films; surfactants zein; effects surfactants ... See more keywords
Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers
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DOI: 10.7150/thno.73966
Abstract: Background: Immune-modulating therapies impart positive outcomes in a subpopulation of cancer patients. Improved delivery strategies and non-invasive monitoring of anti-tumor effects can help enhance those outcomes and understand the mechanisms associated with the generation of… read more here.
Keywords: skin; simultaneous delivery; immune; tumor ... See more keywords