A High-Throughput RP-UPLC Assay for Simultaneous Determination of Telmisartan and Azelnidipine in Pharmaceutical Formulations.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2765
Abstract: Telmisartan, an angiotensin II receptor blocker, and azelnidipine, a dihydropyridine calcium channel blocker, are often co‐prescribed for the effective management of hypertension. The development of accurate and efficient analytical methods is crucial for ensuring the… read more here.
Keywords: azelnidipine pharmaceutical; uplc assay; pharmaceutical formulations; simultaneous determination ... See more keywords
Simultaneous determination of guaifenesin enantiomers and ambroxol HCl using 50-mm chiral column for a negligible environmental impact.
Sign Up to like & getrecommendations! Published in 2019 at "Chirality"
DOI: 10.1002/chir.23116
Abstract: Chiral stationary phases are conveniently used for enantiomeric separation of drugs by liquid chromatography. Consumption of large volumes of hazardous solvents is considered as a common challenge for the sustainability of this technique. To this… read more here.
Keywords: simultaneous determination; ambroxol hcl; column; environmental impact ... See more keywords
A Robust HPLC Method for the Simultaneous Determination of Finerenone and Its Enantiomer Using AQbD.
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DOI: 10.1002/chir.70052
Abstract: The enantiomeric purity of Finerenone (FIN), a novel therapeutic for chronic kidney disease (CKD), is a critical quality attribute for ensuring patient safety. This study reports the first chiral HPLC method for the simultaneous determination… read more here.
Keywords: enantiomer; method; hplc method; finerenone ... See more keywords
Simultaneous determination of mitotane, its metabolite and 5 steroid hormones in urine samples by capillary electrophoresis using β-CD2 SDS1 complexes as hydrophobic compounds solubilizers.
Sign Up to like & getrecommendations! Published in 2021 at "Electrophoresis"
DOI: 10.1002/elps.202100250
Abstract: Mitotane is a cytotoxic drug used in the treatment of inoperable adrenocortical carcinoma (ACC), it inhibits steroidogenesis as well, and therefore monitoring the level of steroid hormones in patients treated with mitotane is a crucial… read more here.
Keywords: simultaneous determination; mitotane; cd2 sds1; steroid hormones ... See more keywords
Simultaneous determination of pyrametostrobin and its two metabolites in cucumber and soil using a quick, easy, cheap, effective, rugged, and safe method with HPLC-MS/MS.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700109
Abstract: An easy, effective and sensitive analytical method for the simultaneous determination of a novel fungicide pyrametostrobin and its two metabolites pyrametostrobin-M1 and pyrametostrobin-M2 in cucumber and soil was developed using a quick, easy, cheap, effective,… read more here.
Keywords: simultaneous determination; cucumber soil; method; two metabolites ... See more keywords
Simultaneous determination of alcohols including diols and triols by HPLC with ultraviolet detection based on the formation of a copper(II) complex.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700635
Abstract: We developed a reversed-phase high-performance liquid chromatography method with ultraviolet detection using on-line complexation with Cu(II) ion for analysis of five alcohols including diols and triol (methanol, ethanol, 1,2-propanediol, 1,3-propanediol, and glycerol). The Cu(II) ion… read more here.
Keywords: simultaneous determination; ultraviolet detection; formation; alcohols including ... See more keywords
A validated LC-MS/MS method for the simultaneous determination of 20-(S)-protopanaxatriol and its two active metabolites in rat plasma: Application to a pharmacokinetics study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700909
Abstract: We present a validated liquid chromatography with tandem mass spectrometry method for simultaneous determination of 20-(S)-protopanaxatriol and its two oxidative stereoisomeric metabolites (20S,24S)-epoxy-dammarane-3,6,12,25-tetraol (M1) and (20S,24R)-epoxy-dammarane-3,6,12,25-tetraol (M2) in rat plasma. 20-(S)-Protopanaxatriol, M1, and M2 were… read more here.
Keywords: simultaneous determination; rat plasma; protopanaxatriol two; method simultaneous ... See more keywords
Rapid method for simultaneous determination of ascorbic acid and zinc in effervescent tablets by capillary zone electrophoresis with contactless conductivity detection.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201801042
Abstract: Ascorbic acid and zinc are essential nutrients that play important roles in nutrition, immune support, and maintenance of health. For this reason, both compounds are widely used as ingredients in dietary supplements. We report, for… read more here.
Keywords: simultaneous determination; detection; ascorbic acid; acid zinc ... See more keywords
Simultaneous determination of five alkaloids from Rauvolfia Vomitoria in rat plasma by LC-MS/MS: application to a comparative pharmacokinetic study in normal and Type 2 diabetic rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202000914
Abstract: Rauvolfia vomitoria is widely distributed in the tropical regions of Africa and Asia, and has been used in traditional folk medicine in China. Indole alkaloids were found to be major bioactive components, while the effects… read more here.
Keywords: simultaneous determination; medicine; determination five; rauvolfia vomitoria ... See more keywords
Green micellar liquid chromatographic method for simultaneous determination of antihistaminic drugs tripelennamine hydrochloride and diphenhydramine in pharmaceutical gel.
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DOI: 10.1002/jssc.202300757
Abstract: A new green micellar liquid chromatographic method has been developed and validated for the simultaneous determination of diphenhydramine (DPH) and tripelennamine hydrochloride (TRP) using a micellar mobile phase consisting of 1 mM Tween 20 in phosphate… read more here.
Keywords: method; green micellar; micellar liquid; simultaneous determination ... See more keywords
Simultaneous Determination of Vancomycin and Creatinine by Dried Plasma Spotsampling via LC-MS/MS.
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DOI: 10.1002/jssc.70279
Abstract: Routine monitoring of vancomycin drug concentrations is crucial for optimizing dosages to ensure therapeutic efficacy and minimize adverse effects. Vancomycin's clearance is highly correlated with creatinine clearance. However, in developing countries, the majority of hospitals… read more here.
Keywords: creatinine dried; dried plasma; vancomycin creatinine; simultaneous determination ... See more keywords