In vitro and in vivo evaluation of chitosan scaffolds combined with simvastatin-loaded nanoparticles for guided bone regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-019-6249-3
Abstract: AbstractThe objective of this study was to fabricate and characterize chitosan combined with different amounts of simvastatin-loaded nanoparticles and to investigate their potential for guided bone regeneration in vitro and in vivo. Different SIM-CSN formulations… read more here.
Keywords: simvastatin loaded; simvastatin; loaded nanoparticles; bone regeneration ... See more keywords
Simvastatin-Loaded Lipid Emulsion Nanoparticles: Characterizations and Applications
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DOI: 10.1021/acsomega.2c02242
Abstract: Simvastatin (SIM) is a diet drug to treat high lipid levels in the blood. It has the drawback of being metabolized in humans’ gastrointestinal tract (GIT) when taken in an oral dosage form. To enhance… read more here.
Keywords: lipid emulsion; nanoparticles characterizations; simvastatin loaded; emulsion nanoparticles ... See more keywords
Simvastatin-Loaded Nanofibrous Membrane Efficiency on the Repair of Achilles Tendons
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s353066
Abstract: Introduction In this study, simvastatin-incorporated poly(D,L-lactide-co-glycolide) (PLGA) nanofibrous mats were fabricated via electrospinning, and their efficacy in the repair of the Achilles tendon was evaluated. Methods The morphology of spun nanofibers and the in vitro… read more here.
Keywords: achilles tendons; loaded nanofibrous; simvastatin loaded; repair achilles ... See more keywords
OPTIMIZATION OF FORMULATION PARAMETERS AND CHARACTERIZATION OF SIMVASTATIN LOADED CHITOSAN NANOPARTICLES.
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DOI: 10.21474/ijar01/3422
Abstract: * N. Selvasudha M. Pharm 1 , Dr. Kailasam Koumaravelou Ph.D. 2 , and N. Sri Durgadevi M.Pharm 3 . 1. Research scholar, PRIST University, Puducherry campus,24/4, Uruvaiyar road, Abishegapakkam, Puducherry. 2. Director, PRIST University,… read more here.
Keywords: formulation parameters; simvastatin loaded; parameters characterization; optimization formulation ... See more keywords
Simvastatin Loaded Nano Hydroxyapatite in Bone Regeneration: A Study in the Rabbit Femoral Condyle.
Sign Up to like & getrecommendations! Published in 2019 at "Current drug delivery"
DOI: 10.2174/1567201816666190610164303
Abstract: BACKGROUND Enhancement of the bone regenerative capacity of the bone substitutes could be achieved by incorporating bioactive agents such as proteins, and different drugs. Simvastatin, an inhibitor of cholesterol synthesis, stimulate bone formation by enhancing… read more here.
Keywords: femoral condyle; simvastatin loaded; bone regeneration; simvastatin ... See more keywords
Simvastatin Loaded Dissolvable Microneedle Patches with Improved Pharmacokinetic Performance
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DOI: 10.3390/mi13081304
Abstract: Microneedle patches (MNPs) are one of the emerging approaches for drug delivery involving minimal invasion and improved skin penetration of macro- and micro-entities. Herein, we report dissolvable microneedle patches (dMNPs) as a novel tool for… read more here.
Keywords: microneedle patches; simvastatin loaded; dissolvable microneedle; loaded dissolvable ... See more keywords