Synthesis, Antitumor of Sinomenine Derivatives and Apoptotic Induction via IL-6/PI3K/Akt/NF-κB Signaling Pathway in MCF-7 Cells.
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DOI: 10.1002/cmdc.202200234
Abstract: Natural products have been widely considered as an important resource for new drugs or lead compounds. Sinomenine (SIN) and its derivatives exert antitumor activity via regulation of inflammatory mediators. For these reasons we synthesized three… read more here.
Keywords: pi3k akt; apoptotic induction; antitumor; antitumor activity ... See more keywords