Sinapic Acid Mitigates Pentylenetetrazol-induced Acute Seizures By Modulating the NLRP3 Inflammasome and Regulating Calcium/calcineurin Signaling: In Vivo and In Silico Approaches
Sign Up to like & getrecommendations! Published in 2024 at "Inflammation"
DOI: 10.1007/s10753-024-02019-0
Abstract: Sinapic acid (SA) is a naturally occurring carboxylic acid found in citrus fruits and cereals. Recent studies have shown that SA has potential anti-seizure properties due to its anti-inflammatory, antioxidant, and anti-apoptotic effects. The present… read more here.
Keywords: calcium calcineurin; ptz; silico; sinapic acid ... See more keywords
Simultaneous extraction and enzymatic hydrolysis of mustard bran for the recovery of sinapic acid
Sign Up to like & getrecommendations! Published in 2021 at "Food and Bioproducts Processing"
DOI: 10.1016/j.fbp.2021.09.003
Abstract: Abstract The simultaneous extraction and enzymatic hydrolysis of sinapine from a mustard residue was designed for the recovery of sinapic acid, a high value-added phenolic acid. An initial screening allowed the identification of sinapoyl esterase… read more here.
Keywords: sinapic; simultaneous extraction; sinapic acid; mustard ... See more keywords
Preparation, development and characterization of Leucaena leucocephala galactomannan (LLG) conjugated sinapic acid: A potential colon targeted prodrug.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.02.132
Abstract: Sinapic acid (SA), a widely prevalent hydroxycinnamic acid, possess numerous biological activities owing to its antioxidant property. The present study was aimed to prepare colon targeted polysaccharidic/polymeric ester prodrug of SA (a microbially triggered system)… read more here.
Keywords: llg; leucaena leucocephala; sinapic acid; colon targeted ... See more keywords
Two distinct enzymatic approaches for coupling fatty acids onto lignocellulosic materials
Sign Up to like & getrecommendations! Published in 2017 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2017.01.008
Abstract: Two enzyme based strategies for hydrophobic functionalization of lignocellulose materials were developed and mechanistically compared using sinapic acid and the dimer syringylglycerol β-guaiacyl ether as models respresenting (hardwood) lignin substructures for coupling fatty acid esters.… read more here.
Keywords: acid esters; coupling fatty; fatty acid; sinapic acid ... See more keywords
Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
Sign Up to like & getrecommendations! Published in 2021 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2021.08.001
Abstract: Abstract Cancer of lung is the utmost typical cause of death and the number of cases is increasing rapidly, which has emerged as a major leading health problem. A large amount of reports suggested that… read more here.
Keywords: cancer; lung cancer; sinapic acid; lung ... See more keywords
Serumal Lipidomics Reveals the Anti-inflammatory Effect of Flax Lignans and Sinapic Acid in High-Fat-Diet-Fed Mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c07291
Abstract: Flax lignans (SDG) and sinapic acid (SA) both have the function of antioxidation and anti-inflammation. However, previous studies have focused mainly on biochemical measurements, gene expression analysis, and clinical assessments. There are limited studies that… read more here.
Keywords: fat diet; flax lignans; sinapic acid; effect ... See more keywords
LC-MS/MS-Guided Discovery of Sinapic Acid Derivatives from Lepidium sativum Seeds and Their Anti-inflammatory Activity.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c03622
Abstract: Edible seeds of Lepidium sativum are known for their health-promoting properties. A total of 17 sinapic acid derivatives, including 12 previously undescribed compounds, were isolated from L. sativum seeds using an LC-MS/MS-guided strategy. Among them,… read more here.
Keywords: lepidium sativum; sinapic acid; sativum seeds; anti inflammatory ... See more keywords
Beta-Sitosterol-Conjugated Sinapic Acid-Engineered Nanoliposome: Biomucoadhesive and Enzyme-Responsive Targeted Oral Therapy in Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c02190
Abstract: Developing oral drug delivery systems is promising for ulcerative colitis (UC). However, the key challenges, including formulation degradation under harsh gastric conditions, poor targeting efficiency, and limited colonic residence, lead to poor therapeutic efficacy that… read more here.
Keywords: enzyme responsive; ulcerative colitis; beta sitosterol; sinapic acid ... See more keywords
Sinapic acid reduces ischemia/reperfusion injury due to testicular torsion/detorsion in rats
Sign Up to like & getrecommendations! Published in 2021 at "Andrologia"
DOI: 10.1111/and.14117
Abstract: This study aimed to investigate the protective effect of sinapic acid (SA) on biochemical and histopathological changes in an experimental testicular torsion‐detorsion rat model. Twenty‐four rats were randomised into four groups: sham group, ischemia/reperfusion (IR)… read more here.
Keywords: reperfusion; testicular torsion; sinapic acid; torsion detorsion ... See more keywords
Sinapic acid ameliorates cisplatin‐induced disruptions in testicular steroidogenesis and spermatogenesis by modulating androgen receptor, proliferating cell nuclear antigen and apoptosis in male rats
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14369
Abstract: The chemotherapeutic cisplatin, which is widely used in many cancer types, causes testicular toxicity. Sinapic acid has many therapeutic effects such as antioxidant, anti‐inflammatory and antihyperglycaemic. This study aimed to investigate the improving effects of… read more here.
Keywords: sinapic acid; toxicity; group; cisplatin induced ... See more keywords
Anticancer Activity of Sinapic Acid by Inducing Apoptosis in HT-29 Human Colon Cancer Cell Line.
Sign Up to like & getrecommendations! Published in 2023 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0523
Abstract: Colorectal cancer is the third most lethal and fourth most commonly diagnosed cancer worldwide. Sinapic acid, a derivative of hydroxycinnamic acid, is a promising phytochemical exhibiting numerous pharmacological activities in various systems. It is a… read more here.
Keywords: sinapic acid; acid; cancer; cell line ... See more keywords