The intriguing role of USP30 inhibitors as deubiquitinating enzymes from the patent literature since 2013.
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DOI: 10.1080/13543776.2022.2003780
Abstract: INTRODUCTION : Ubiquitin specific peptidase 30 (USP30) is a mitochondrial deubiquitinase that antagonizes ubiquitination-mediated mitophagy of damaged or impaired mitochondria driven by the activity of PARK2/Parkin ubiquitin ligase and PINK1 protein kinase. Researchers have related… read more here.
Keywords: usp30 inhibitors; small molecule; since 2013; patent literature ... See more keywords