TF protein of Sindbis virus antagonizes host type I interferon responses in a palmitoylation-dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Virology"
DOI: 10.1016/j.virol.2020.01.001
Abstract: Sindbis virus (SINV) produces the small membrane protein TF from the 6K gene via a (-1) programmed ribosomal frameshifting. While several groups have shown that TF-deficient virus exhibits reduced virulence, the mechanism(s) by which this… read more here.
Keywords: palmitoylation; interferon; host; type ... See more keywords
Confocal Analysis of the Distribution and Persistence of Sindbis Virus (TaV-GFP) Infection in Midguts of Aedes aegypti Mosquitoes
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927620001270
Abstract: Abstract Biological transmission of arthropod-borne viruses (arboviruses) to vertebrate hosts by hematophagous insects poses a global threat because such arboviruses can result in a range of serious public health infectious diseases. Sindbis virus (SINV), the… read more here.
Keywords: tav gfp; virus; pmg; sindbis virus ... See more keywords
Sindbis virus is suppressed in the yellow fever mosquito aedes aegypti by Atg6/BECN1 (autophagy-related 6)-mediated activation of autophagy.
Sign Up to like & getrecommendations! Published in 2025 at "Autophagy"
DOI: 10.1080/15548627.2025.2523735
Abstract: ABSTRACT Macroautophagy/autophagy is a critical modulator of pathogen invasion response in vertebrates and invertebrates. However, how it affects mosquito-borne viral pathogens that significantly burden public health remains relatively underexplored. To address this gap, we use… read more here.
Keywords: virus; sindbis virus; autophagy; fever mosquito ... See more keywords
Treatment of Sindbis Virus-Infected Neurons with Antibody to E2 Alters Synthesis of Complete and nsP1-Expressing Defective Viral RNAs
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02221-22
Abstract: Alphaviruses are important causes of viral encephalomyelitis without approved treatments or vaccines. Antibody to the Sindbis virus (SINV) E2 glycoprotein is required for immune-mediated noncytolytic virus clearance from neurons. ABSTRACT Alphaviruses are positive-sense RNA viruses… read more here.
Keywords: dvg; rna; sindbis virus; sinv ... See more keywords
Sindbis virus outbreak and evidence for geographical expansion in Finland, 2021
Sign Up to like & getrecommendations! Published in 2022 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2022.27.31.2200580
Abstract: Sindbis virus (SINV) caused a large outbreak in Finland in 2021 with 566 laboratory-confirmed human cases and a notable geographical expansion. Compared with the last large outbreak in 2002, incidence was higher in several hospital… read more here.
Keywords: geographical expansion; finland 2021; sindbis virus; finland ... See more keywords
Towards modelling tick-virus interactions using the weakly pathogenic Sindbis virus: Evidence that ticks are competent vectors
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2024.1334351
Abstract: Most tick-borne viruses (TBVs) are highly pathogenic and require high biosecurity, which severely limits their study. We found that Sindbis virus (SINV), predominantly transmitted by mosquitoes, can replicate in ticks and be subsequently transmitted, with… read more here.
Keywords: tick virus; virus; sindbis virus; infection ... See more keywords
Serological Survey of Mosquito-Borne Arboviruses in Wild Birds from Important Migratory Hotspots in Romania
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11111270
Abstract: In the context of climate change, globalization, and enhanced human traveling, arboviruses continue to represent a threat to public health. West Nile and Usutu viruses are mosquito-borne viruses belonging to the Flaviviridae family (Flavivirus genus)… read more here.
Keywords: serological survey; wild birds; west nile; mosquito borne ... See more keywords
Presence of Antibodies against Sindbis Virus in the Israeli Population: A Nationwide Cross-Sectional Study
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11060542
Abstract: Sindbis virus (SINV) is a mosquito-borne alphavirus circulating globally. SINV outbreaks have been mainly reported in North-European countries. In Israel, SINV was detected in 6.3% of mosquito pools; however, SINV infection in humans has rarely… read more here.
Keywords: sinv; sindbis virus; sinv igg; israeli population ... See more keywords
Rescue of Infectious Sindbis Virus by Yeast Spheroplast-Mammalian Cell Fusion
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13040603
Abstract: Sindbis virus (SINV), a positive-sense single stranded RNA virus that causes mild symptoms in humans, is transmitted by mosquito bites. SINV reverse genetics have many implications, not only in understanding alphavirus transmission, replication cycle, and… read more here.
Keywords: rescue infectious; rescue; yeast; fusion ... See more keywords
Detection and Isolation of Sindbis Virus from Field Collected Mosquitoes in Timimoun, Algeria
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DOI: 10.3390/v14050894
Abstract: Sindbis virus (SINV) is a zoonotic alphavirus (family Togaviridae, genus Alphavirus) that causes human diseases in Africa, Europe, Asia, and Australia. Occasionally, SINV outbreaks were reported in South Africa and northern Europe. Birds are the… read more here.
Keywords: field collected; collected mosquitoes; virus field; isolation sindbis ... See more keywords
Vertical Transmission of Sindbis Virus in Culex Mosquitoes
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14091915
Abstract: Simple Summary The transmission of vector-borne viruses requires arthropod vectors that are actively seeking for new blood-meal hosts. In regions where vectors do not blood-feed for prolonged periods, the persistence of a virus depends on… read more here.
Keywords: field; sindbis virus; vertical transmission; transmission ... See more keywords