Transcriptomics analysis reveals candidate genes and pathways for susceptibility or resistance to Singapore grouper iridovirus in orange-spotted grouper (Epinephelus coioides)
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.09.003
Abstract: ABSTRACT In this study, the transcriptional response of grouper to Singapore grouper iridovirus (SGIV) stimulation was characterized using RNA sequencing. Transcriptome sequencing of three test groups in the grouper was performed using the Illumina MiSeq… read more here.
Keywords: susceptibility; grouper; singapore grouper; group ... See more keywords
Segmentation and Comparative Modeling in an 8.6-Å Cryo-EM Map of the Singapore Grouper Iridovirus.
Sign Up to like & getrecommendations! Published in 2019 at "Structure"
DOI: 10.1016/j.str.2019.08.002
Abstract: SGIV, or Singapore grouper iridovirus, is a large double-stranded DNA virus, reaching a diameter of 220 nm and packaging a genome of 140 kb. We present a 3D cryoelectron microscopy (cryo-EM) icosahedral reconstruction of SGIV determined… read more here.
Keywords: comparative modeling; singapore grouper; segmentation; cryo map ... See more keywords
Grouper TRADD Mediates Innate Antiviral Immune Responses and Apoptosis Induced by Singapore Grouper Iridovirus (SGIV) Infection
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00329
Abstract: Tumor necrosis factor (TNF) receptor type 1-associated DEATH domain protein (TRADD) is a TNFR1-associated signal transducer and an essential component of the TNFR1 complex that is involved in activating both apoptotic and nuclear factor (NF)-κB… read more here.
Keywords: apoptosis; grouper; singapore grouper; tradd ... See more keywords
Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.01446
Abstract: Autophagy is a conserved catabolic process that occurs at basal levels to maintain cellular homeostasis. Most virus infections can alter the autophagy level, which functions as either a pro-viral or antiviral pathway, depending on the… read more here.
Keywords: singapore grouper; iridovirus sgiv; inhibited autophagy; sgiv inhibited ... See more keywords