Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202408878
Abstract: Haploinsufficiency of the ATP6V1B2, a subunit of V‐ATPases, underlies genetic disorders including Dominant deafness‐onychodystrophy (DDOD), deafness, onychodystrophy, osteodystrophy, mental retardation and seizures (DOORS), and Zimmermann‐Laband syndromes, all characterized by congenital hearing loss and onychodystrophy. Effective… read more here.
Keywords: single administration; loss; aav; hair ... See more keywords
Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of physical medicine and rehabilitation"
DOI: 10.1016/j.apmr.2016.11.013
Abstract: OBJECTIVE To examine the effects of a single administration of focused extracorporeal shock wave therapy on eccentric exercise-induced delayed-onset muscle soreness (DOMS). DESIGN Three-arm randomized controlled study. SETTING University research center. PARTICIPANTS Participants (N=46; 23… read more here.
Keywords: single administration; muscle; focused extracorporeal; extracorporeal shock ... See more keywords
A single administration of a long-acting recombinant ovine FSH (roFSH) for cattle superovulation.
Sign Up to like & getrecommendations! Published in 2020 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2020.04.037
Abstract: A recombinant long-acting ovine follicle stimulating hormone (roFSH) has been devised and its biological effectiveness following a single dose has been assessed in several experiments under field conditions, in pasture-based beef and dairy farming in… read more here.
Keywords: administration long; single administration; long acting; ovine ... See more keywords
Single-Administration Long-Acting Microarray Patch with Ultrahigh Loading Capacity and Multiple Releases of Thermally Stable Antibodies
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00919
Abstract: Current antibody (Ab) therapies require development of stable formulations and an optimal delivery system. Here, we present a new strategy to create a single-administration long-lasting Ab-delivery microarray (MA) patch, which can carry high doses of… read more here.
Keywords: administration long; microarray patch; single administration;
Cationic amino acid-engineered peptide hydrogels for sustained and potent antigen delivery enabling single-administration vaccination.
Sign Up to like & getrecommendations! Published in 2025 at "Nanoscale"
DOI: 10.1039/d5nr03790e
Abstract: Peptide hydrogels have attracted considerable interest as vaccine delivery systems. This study systematically investigates how cationic residues affect peptide hydrogel-mediated antigen delivery and immune response, as well as the possibility of achieving single-dose immunization. Here,… read more here.
Keywords: single administration; gel; antigen; peptide hydrogels ... See more keywords
Blood Pressure and Cognitive Performance After a Single Administration of a Camphor-Crataegus Combination in Adolescents with Low Blood Pressure.
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DOI: 10.1055/a-0634-6597
Abstract: Low blood pressure is rather widespread among adolescents and frequently accompanied by complaints. Two single-center, double-blinded, randomized, and placebo-controlled trials were performed with adolescent participants in the age range of 14 - 17 y having a systolic blood… read more here.
Keywords: blood; low blood; blood pressure; single administration ... See more keywords
Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyac205
Abstract: BACKGROUND Clinical guidelines recommend antipsychotics for the treatment of delirium; however, there has been no confirmed recommendation regarding their administrating patterns. This study aims to investigate whether different dosing patterns of antipsychotics (single or multiple… read more here.
Keywords: oncology; single administration; administration; delirium ... See more keywords
A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006591
Abstract: Key Points • A single hIL-7-hyFc administration induced a sustained increase in the numbers of T cells, but not regulatory T cells, in healthy adults.• The effector functions of antigen-specific CD8+ T cells were preserved… read more here.
Keywords: administration; single administration; hil hyfc; effector functions ... See more keywords
Infectious complications related to radiofrequency ablation of liver tumors: The role of antibiotics
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DOI: 10.1371/journal.pone.0259641
Abstract: Background and aim Prophylactic administration of antibiotics within 24 hours of surgery is recommended to reduce the risk of infection. We conducted a prospective study to compare the efficacy of single administration of antibiotics with… read more here.
Keywords: administration; complications related; single administration; protocol ... See more keywords