Articles with "single allele" as a keyword



Single allele Lmbrd1 knockout results in cardiac hypertrophy.

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Published in 2018 at "Journal of the Formosan Medical Association = Taiwan yi zhi"

DOI: 10.1016/j.jfma.2017.05.002

Abstract: BACKGROUND/PURPOSE LMBD1 protein, a type IV-B plasma membrane protein possessing nine putative trans-membrane domains, was previously demonstrated at cellular level to play a critical part in the signaling cascade of insulin receptor through its involvement… read more here.

Keywords: cardiac hypertrophy; single allele; lmbrd1; allele lmbrd1 ... See more keywords

guidedNOMe-seq quantifies chromatin states at single allele resolution for hundreds of custom regions in parallel

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Published in 2024 at "BMC Genomics"

DOI: 10.1186/s12864-024-10625-3

Abstract: Since the introduction of next generation sequencing technologies, the field of epigenomics has evolved rapidly. However, most commonly used assays are enrichment-based methods and thus only semi-quantitative. Nucleosome occupancy and methylome sequencing (NOMe-seq) allows for… read more here.

Keywords: states single; single allele; resolution; chromatin states ... See more keywords