Articles with "single cell" as a keyword



From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

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Published in 2025 at "Febs Letters"

DOI: 10.1002/1873-3468.70162

Abstract: This study, based on datasets from healthy tissues, lactating mammary epithelial cells, and breast cancer phenotypes, investigates mammary gland pathophysiology at single‐cell resolution to identify key regulators in breast cancer development and to gain a… read more here.

Keywords: breast cancer; breast; single cell; cell resolution ... See more keywords

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

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Published in 2025 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.70061

Abstract: Diabetes mellitus (DM) is among the most prevalent metabolic diseases worldwide, associated with an increased risk of mortality. Although numerous studies have been conducted to uncover the cellular and molecular pathways associated with DM pathogenesis,… read more here.

Keywords: diabetes mellitus; cell rna; rna sequencing; single cell ... See more keywords

Single Cell Transcriptomes Derived from Human Cervical and Uterine Tissue during Pregnancy

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Published in 2019 at "Advanced Biosystems"

DOI: 10.1002/adbi.201800336

Abstract: This work presents the workflow for generating single cell transcriptomes derived from primary human uterine and cervical tissue obtained during planned cesarean hysterectomies. In total, a catalogue of 310 single cell transcriptomes are obtained, cell… read more here.

Keywords: single cell; tissue; cell transcriptomes; transcriptomes derived ... See more keywords
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Technological Advances in Multiscale Analysis of Single Cells in Biomedicine

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Published in 2019 at "Advanced Biosystems"

DOI: 10.1002/adbi.201900138

Abstract: Single‐cell analysis has recently received significant attention in biomedicine. With the advances in super‐resolution microscopy, fluorescence labeling, and nanoscale biosensing, new information may be obtained for the design of cancer diagnosis and therapeutic interventions. The… read more here.

Keywords: single cell; analysis; analysis single; multiscale analysis ... See more keywords
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Simultaneous Single Cell Gene Expression and EGFR Mutation Analysis of Circulating Tumor Cells Reveals Distinct Phenotypes in NSCLC

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Published in 2020 at "Advanced Biosystems"

DOI: 10.1002/adbi.202000110

Abstract: While cancer cell populations are known to be highly heterogeneous within a tumor, the current gold standard of tumor profiling is through a tumor biopsy. These biopsies are invasive and prone to missing these clones… read more here.

Keywords: single cell; analysis; gene expression; cell ... See more keywords

Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro- and Macroenvironments.

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Published in 2017 at "Advanced healthcare materials"

DOI: 10.1002/adhm.201600913

Abstract: Modular bioinks based on single cell microgels within distinct injectable prepolymers enable uncoupling of biomaterials' micro- and macroenvironments. These inks allow biofabrication of 3D constructs that recapitulate the multiscale modular design of native tissues with… read more here.

Keywords: single cell; modular bioinks; cell microgel; microgel based ... See more keywords

A Decade of Advances in Single-Cell Nanocoating for Mammalian Cells.

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Published in 2021 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202100347

Abstract: Strategic advances in the single-cell nanocoating of mammalian cells have noticeably been made during the last decade, and many potential applications have been demonstrated. Various cell-coating strategies have been proposed via adaptation of reported methods… read more here.

Keywords: single cell; decade; nanocoating mammalian; mammalian cells ... See more keywords

High‐Throughput, Living Single‐Cell, Multiple Secreted Biomarker Profiling Using Microfluidic Chip and Machine Learning for Tumor Cell Classification

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Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202102800

Abstract: Secreted proteins provide abundant functional information on living cells and can be used as important tumor diagnostic markers, of which profiling at the single‐cell level is helpful for accurate tumor cell classification. Currently, achieving living… read more here.

Keywords: living single; cell; cell classification; single cell ... See more keywords

Single‐Cell Liquid‐Core Microcapsules for Biomedical Applications

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202403808

Abstract: More recently, single‐cell encapsulation emerged as a promising field in biomedicine due to its potential applications, in cell analysis and therapy. Traditional techniques involve embedding cells in crosslinked polymers to create continuous microgels, suitable mainly… read more here.

Keywords: core microcapsules; single cell; analysis; cell ... See more keywords

Multicolor and 3D Holography Generated by Inverse‐Designed Single‐Cell Metasurfaces

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Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202208520

Abstract: Metasurface‐generated holography has emerged as a promising route for fully reproducing vivid scenes by manipulating the optical properties of light using ultra‐compact devices. However, achieving multiple holographic images using a single metasurface is still difficult… read more here.

Keywords: inverse; cell metasurfaces; holography; design ... See more keywords

User‐Controlled 4D Biomaterial Degradation with Substrate‐Selective Sortase Transpeptidases for Single‐Cell Biology

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Published in 2023 at "Advanced Materials"

DOI: 10.1002/adma.202209904

Abstract: Stimuli‐responsive biomaterials show great promise for modeling disease dynamics ex vivo with spatiotemporal control over the cellular microenvironment. However, harvesting cells from such materials for downstream analysis without perturbing their state remains an outstanding challenge… read more here.

Keywords: cell; sortase; single cell; substrate ... See more keywords