Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of TRIM22
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DOI: 10.1136/gutjnl-2016-312742
Abstract: Objective Interferons (IFNs) mediate direct antiviral activity. They play a crucial role in the early host immune response against viral infections. However, IFN therapy for HBV infection is less effective than for other viral infections.… read more here.
Keywords: response; hbv; methylation utr; single cpg ... See more keywords
The Effect of Single CpG Demethylation on the Pattern of DNA-Protein Binding
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DOI: 10.3390/ijms20040914
Abstract: Epidermal differentiation is a complex process and its regulation may involve epigenetic factors. Analysis of DNA methylation in 20 selected regions within the epidermal differentiation complex (EDC) gene cluster by targeted next-generation sequencing (NGS) detected… read more here.
Keywords: cpg demethylation; dna; demethylation; single cpg ... See more keywords