Two Single Drug Fatal Intoxications By Mitragynine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac016
Abstract: Mitragyna speciosa, a species of plant that is native to Thailand, Malaysia and Southeast Asia, contains two major psychoactive alkaloids: mitragynine and 7-hydroxymitragynine. Pharmacologically, the alkaloids exhibit biphasic effects - at low dose, stimulant effects… read more here.
Keywords: toxicology; two single; single drug; intoxications mitragynine ... See more keywords
Single versus multi-drug antimicrobial surgical infection prophylaxis for left ventricular assist devices: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Artificial organs"
DOI: 10.1111/aor.13441
Abstract: Infection remains the Achilles heel of left ventricular assist device (LVAD) therapy. However, an optimal antimicrobial surgical infection prophylaxis (SIP) regimen has not been established. This study evaluated the efficacy of a single-drug SIP compared… read more here.
Keywords: single drug; infection; drug; multi drug ... See more keywords
GestaTIonal TrophoblAstic NeoplasIa Ultrasound assessMent: TITANIUM study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-000434
Abstract: Background There are limited data on ultrasound morphologic features of gestational trophoblastic neoplasia. A predictive model to determine predictors of response to therapy would be ideal in the management of patients with this rare disease.… read more here.
Keywords: single drug; risk; study; gestational trophoblastic ... See more keywords
Effect of Apatinib Combined with Seggio on the Expression of Serum AFP and CA724 and Long-Term Survival Rate in Patients with Advanced Gastric Cancer Undergoing Comfortable Nursing Intervention
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/2004973
Abstract: Objective To study the effect of apatinib combined with seggio on the expression of serum AFP and CA724 and the long-term survival rate in advanced gastric cancer patients undergoing comfort nursing intervention. Methods 98 advanced… read more here.
Keywords: joint group; single drug; drug group; ca724 ... See more keywords
MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index
Sign Up to like & getrecommendations! Published in 2020 at "BMC Cancer"
DOI: 10.1186/s12885-020-6643-8
Abstract: Background Treatment resistance is a major clinical challenge of diffuse large B-cell lymphoma (DLBCL) where approximately 40% of the patients have refractory disease or relapse. Since DLBCL is characterized by great clinical and molecular heterogeneity,… read more here.
Keywords: single drug; dlbcl; mir; drug ... See more keywords
A novel network based linear model for prioritization of synergistic drug combinations
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DOI: 10.1371/journal.pone.0266382
Abstract: Drug combination therapies can improve drug efficacy, reduce drug dosage, and overcome drug resistance in cancer treatments. Current research strategies to determine which drug combinations have a synergistic effect rely mainly on clinical or empirical… read more here.
Keywords: single drug; novel network; drug combinations; synergistic drug ... See more keywords
Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.894960
Abstract: Medical Cannabis and its major cannabinoids (−)-trans-Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are gaining momentum for various medical purposes as their therapeutic qualities are becoming better established. However, studies regarding their efficacy are oftentimes inconclusive. This… read more here.
Keywords: versatile plant; cannabis; single drug; plant rather ... See more keywords
Single-Drug Approach with Edoxaban is Effective for Resolving Non-Acute Cancer-Associated Venous Thrombosis: A Single-Arm Retrospective Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12071711
Abstract: Recently, cancer-related venous thromboembolism (VTE) has been termed “cancer-associated thrombosis (CAT)” and is the focus of current research. We retrospectively investigated the efficacy of a single-drug approach with edoxaban for the treatment of non-acute CAT.… read more here.
Keywords: single drug; approach edoxaban; drug approach; cancer ... See more keywords