Impact of single-heterozygous UGT1A1 on the clinical outcomes of irinotecan monotherapy after fluoropyrimidine and platinum-based combination therapy for gastric cancer: a multicenter retrospective study
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DOI: 10.1007/s10147-020-01720-y
Abstract: It is unclear whether the UGT1A1 status, single heterozygous (SH) or wild type (WT), is associated with the efficacy and toxicity of irinotecan monotherapy in advanced gastric cancer (AGC). We investigated the association between clinical… read more here.
Keywords: irinotecan monotherapy; clinical outcomes; gastric cancer; single heterozygous ... See more keywords