Profiling of mitochondrial heteroplasmy in single human oocytes by next‐generation sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23655
Abstract: Mitochondrial DNA (mtDNA) plays a crucial role in the development of a competent oocyte. Indeed, mtDNA alterations may predispose to chromosome nondisjunction, resulting in infertility due to a reduced vitality and quality of oocytes and… read more here.
Keywords: human oocytes; single human; mtdna; next generation ... See more keywords
A Single Human Neuron Approach to Synapse Function.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2019.05.005
Abstract: To understand human neuronal function, it is crucial to obtain knowledge of how human synapses operate. New approaches are necessary to define the unique properties of human synapses. Recently, new culturing approaches have been developed… read more here.
Keywords: human neuron; approach synapse; neuron approach; single human ... See more keywords
Time-of-Flight Fragmentation Spectra Generated by the Proteomic Analysis of Single Human Cells Do Not Exhibit Atypical Fragmentation Patterns.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00715
Abstract: Recent work detailed the unique characteristics of fragmentation spectra derived from peptides from single human cells. This valuable report utilized an ultrahigh-field Orbitrap and directly compared the spectra obtained from high-concentration bulk cell HeLa lysates… read more here.
Keywords: fragmentation; human cells; time flight; fragmentation spectra ... See more keywords
Angle-resolved light scattering of single human chromosomes: experiments and simulations.
Sign Up to like & getrecommendations! Published in 2019 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/aafd6f
Abstract: Angle-resolved light scattering measurements of human metaphase chromosomes were compared to the results of numerical light scattering simulations with geometrical models based on atomic force microscopy (AFM) measurements of the same chromosomes. The simulations were… read more here.
Keywords: resolved light; scattering single; angle resolved; single human ... See more keywords
Clinical benefit for cryopreservation of single human spermatozoa for ICSI: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Andrology"
DOI: 10.1111/andr.13091
Abstract: BACKGROUND Systematic reviews have focused on sperm recovery and post-thaw parameters after cryopreservation, but there no information on the associated clinical outcomes. In recent years, an increasing number of studies have reported cryopreservation of a… read more here.
Keywords: recovery; cryopreservation single; human spermatozoa; single human ... See more keywords