Plasma alpha‐synuclein detected by single molecule array is increased in PD
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.729
Abstract: We utilized ultrasensitive single molecule technology to measure plasma alpha‐synuclein in 221 subjects (51 controls, 170 PD). Plasma alpha‐synuclein levels were significantly higher in PD than controls (15506.3 vs. 13057.0 pg/mL, P = 0.037), adjusting… read more here.
Keywords: plasma alpha; alpha synuclein; single molecule; alpha ... See more keywords
Rapid Prediction of Energy Level Alignment and Conductance of Single‐Molecule Junctions Through Intramolecular Dipole Moment
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202403836
Abstract: How substituents affect the conductance of single‐molecule junctions has been a subject of ongoing debate. Here, a comparative study on the transport properties across a broader range of experimentally proposed and representative π‐conjugated molecular systems,… read more here.
Keywords: molecule junctions; conductance; dipole moment; conductance single ... See more keywords
Topological Engineering of Exceptional Points for Label‐Free Single‐Molecule Detection
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202511772
Abstract: The topological structures around exceptional points (EPs) exhibit enhanced sensitivity for label‐free biosensors. However, the challenge of modifying the intrinsic topology to increase EP biosensor sensitivity remains unresolved. Here, topologically engineered EPs are utilized in… read more here.
Keywords: detection; exceptional points; topology; sensitivity ... See more keywords
Two‐in‐One Molecule as a Single‐Molecule Exciplex Host for Enhancing Solution‐Processed TADF‐OLED Performance
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202513345
Abstract: Exciplexes that exhibit efficient reverse intersystem crossing have attracted considerable attention as host materials for high‐performance organic light‐emitting diodes (OLEDs). However, conventional binary exciplexes, composed of p‐ and n‐type hosts and typically designed for vacuum… read more here.
Keywords: single molecule; exciplex host; solution processed; host ... See more keywords
Plasmonic-Nanopore Biosensors for Superior Single-Molecule Detection.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201900422
Abstract: Plasmonic and nanopore sensors have separately received much attention for achieving single-molecule precision. A plasmonic "hotspot" confines and enhances optical excitation at the nanometer length scale sufficient to optically detect surface-analyte interactions. A nanopore biosensor… read more here.
Keywords: detection; nanopore biosensors; single molecule; plasmonic nanopore ... See more keywords
A Single‐Molecule Memristor based on an Electric‐Field‐Driven Dynamical Structure Reconfiguration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204827
Abstract: A robust single‐molecule memristor is prepared by covalently integrating one phenol molecule with multiple binding sites into nanogapped graphene electrodes. Multilevel resistance switching is realized by the electric‐field‐manipulated reconfiguration of the acyl moiety on the… read more here.
Keywords: electric field; single molecule; molecule memristor; molecule ... See more keywords
A Tunable Single‐Molecule Light‐Emitting Diode with Single‐Photon Precision
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202209750
Abstract: A robust single‐molecule light‐emitting diode (SM‐LED) with high color purity, linear polarization, and efficiency tunability is prepared by covalently integrating one fluorescent molecule into nanogapped graphene electrodes. Furthermore, single‐molecule Förster resonance energy transfer from the… read more here.
Keywords: single molecule; molecule; molecule light; single photon ... See more keywords
Solid-State Quad-Nanopore Array for High-resolution Single-Molecule Analysis and Discrimination.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211399
Abstract: The ability to detect and distinguish biomolecules at the single-molecule level is at the forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time of individual biomolecules in the sensing spot can greatly… read more here.
Keywords: single molecule; solid state; quad; nanopore array ... See more keywords
Exploring Electronic Characteristics of Acceptor-Donor-Acceptor type Molecules by Single-Molecule Charge Transport.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202301876
Abstract: The electronic characteristics of organic optoelectronic materials determine the performance of corresponding devices. Clarifying the relationship between molecular structure and electronic characteristics at the single-molecule level can help to achieve high performance for organic optoelectronic… read more here.
Keywords: single molecule; acceptor; electronic characteristics; molecule ... See more keywords
Nanopore-Based Label-Free and Single-Molecule Sequencing toward Precision Diagnosis.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202513613
Abstract: Nanopore-based single-molecule sequencing (SMS) is a powerful tool for acquiring detailed heterogeneous information on critical building blocks of life, such as nucleic acids, proteins, and a wide array of biomolecules, at the single-molecule level. Real-time… read more here.
Keywords: nanopore based; precision diagnosis; single molecule;
Sheathed Molecular Junctions for Unambiguous Determination of Charge‐Transport Properties
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202300133
Abstract: Future applications of single‐molecular and large‐surface area molecular devices require a thorough understanding and control of molecular junctions, interfacial phenomena, and intermolecular interactions. In this contribution the concept of single‐molecule junction and host‐guest complexation to… read more here.
Keywords: single molecule; molecular wire; molecular junctions; microscopy ... See more keywords