Plasma alpha‐synuclein detected by single molecule array is increased in PD
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.729
Abstract: We utilized ultrasensitive single molecule technology to measure plasma alpha‐synuclein in 221 subjects (51 controls, 170 PD). Plasma alpha‐synuclein levels were significantly higher in PD than controls (15506.3 vs. 13057.0 pg/mL, P = 0.037), adjusting… read more here.
Keywords: plasma alpha; alpha synuclein; single molecule; alpha ... See more keywords
Plasmonic-Nanopore Biosensors for Superior Single-Molecule Detection.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201900422
Abstract: Plasmonic and nanopore sensors have separately received much attention for achieving single-molecule precision. A plasmonic "hotspot" confines and enhances optical excitation at the nanometer length scale sufficient to optically detect surface-analyte interactions. A nanopore biosensor… read more here.
Keywords: detection; nanopore biosensors; single molecule; plasmonic nanopore ... See more keywords
A Single‐Molecule Memristor based on an Electric‐Field‐Driven Dynamical Structure Reconfiguration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204827
Abstract: A robust single‐molecule memristor is prepared by covalently integrating one phenol molecule with multiple binding sites into nanogapped graphene electrodes. Multilevel resistance switching is realized by the electric‐field‐manipulated reconfiguration of the acyl moiety on the… read more here.
Keywords: electric field; single molecule; molecule memristor; molecule ... See more keywords
A Tunable Single‐Molecule Light‐Emitting Diode with Single‐Photon Precision
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202209750
Abstract: A robust single‐molecule light‐emitting diode (SM‐LED) with high color purity, linear polarization, and efficiency tunability is prepared by covalently integrating one fluorescent molecule into nanogapped graphene electrodes. Furthermore, single‐molecule Förster resonance energy transfer from the… read more here.
Keywords: single molecule; molecule; molecule light; single photon ... See more keywords
Solid-State Quad-Nanopore Array for High-resolution Single-Molecule Analysis and Discrimination.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211399
Abstract: The ability to detect and distinguish biomolecules at the single-molecule level is at the forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time of individual biomolecules in the sensing spot can greatly… read more here.
Keywords: single molecule; solid state; quad; nanopore array ... See more keywords
Exploring Electronic Characteristics of Acceptor-Donor-Acceptor type Molecules by Single-Molecule Charge Transport.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202301876
Abstract: The electronic characteristics of organic optoelectronic materials determine the performance of corresponding devices. Clarifying the relationship between molecular structure and electronic characteristics at the single-molecule level can help to achieve high performance for organic optoelectronic… read more here.
Keywords: single molecule; acceptor; electronic characteristics; molecule ... See more keywords
Sheathed Molecular Junctions for Unambiguous Determination of Charge‐Transport Properties
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202300133
Abstract: Future applications of single‐molecular and large‐surface area molecular devices require a thorough understanding and control of molecular junctions, interfacial phenomena, and intermolecular interactions. In this contribution the concept of single‐molecule junction and host‐guest complexation to… read more here.
Keywords: single molecule; molecular wire; molecular junctions; microscopy ... See more keywords
Design of Single‐Molecule Multiferroics for Efficient Ultrahigh‐Density Nonvolatile Memories
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201801572
Abstract: Abstract It is known that an isolated single‐molecule magnet tends to become super‐paramagnetic even at an ultralow temperature of a few Kelvin due to the low spin switching barrier. Herein, single‐molecule ferroelectrics/multiferroics is proposed, as… read more here.
Keywords: molecule; single molecule; molecule multiferroics; density ... See more keywords
Dual Modulation of Single Molecule Conductance via Tuning Side Chains and Electric Field with Conjugated Molecules Entailing Intramolecular O•••S Interactions
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105667
Abstract: Herein, single‐molecule conductance studies of TBT1‐TBT6 which entails 1,4‐dithienylbenzene as the backbone and SMe groups as the anchoring units, with the scanning tunneling microscope break junction (STM‐BJ) technique, are reported. The molecular conductance of TBT1… read more here.
Keywords: electric field; single molecule; conductance; molecule conductance ... See more keywords
High Electrochemiluminescence from Ru(bpy)3 2+ Embedded Metal–Organic Frameworks to Visualize Single Molecule Movement at the Cellular Membrane
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204715
Abstract: Direct imaging of single‐molecule and its movement is of fundamental importance in biology, but challenging. Herein, aided by the nanoconfinement effect and resultant high reaction activity within metal–organic frameworks (MOFs), the designed Ru(bpy)32+ embedded MOF… read more here.
Keywords: single molecule; molecule movement; molecule; metal organic ... See more keywords
Single‐molecule approaches reveal outer membrane protein biogenesis dynamics
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200149
Abstract: Outer membrane proteins (OMPs) maintain the viability of Gram‐negative bacteria by functioning as receptors, transporters, ion channels, lipases, and porins. Folding and assembly of OMPs involves synchronized action of chaperones and multi‐protein machineries which escort… read more here.
Keywords: single molecule; outer membrane; molecule approaches; biogenesis ... See more keywords