Review of the use of nanodevices to detect single molecules.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2022.114645
Abstract: The development of methodologies to identify single molecules and/or to detect/monitor molecular behavior at the single-molecule level is one of the important research topics in chemistry and biology. In this review, we summarized the state-of-the-art… read more here.
Keywords: single molecules; use nanodevices; molecule measurement; review use ... See more keywords
Single Molecules in Focus: From RNA Splicing to Silencing
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.054
Abstract: Nature and Nanotechnology likewise employ nanoscale machines that self-assemble into structures of complex architecture and functionality. Fluorescence microscopy offers a non-invasive tool to probe and ultimately dissect and control these nanoassemblies in real-time. In particular,… read more here.
Keywords: molecule; single molecule; single molecules; molecules focus ... See more keywords
Tracking Single Molecules in Biomembranes: Is Seeing Always Believing?
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.9b07445
Abstract: The spatial organization of molecules in cell membranes and their dynamic interactions play a central role in regulating cell functions. Single-particle tracking (SPT), a technique in which single molecules are imaged and tracked in real… read more here.
Keywords: biomembranes seeing; single molecules; cell membranes; tracking single ... See more keywords
Relocating Single Molecules in Super-Resolved Fluorescence Lifetime Images near a Plasmonic Nanostructure
Sign Up to like & getrecommendations! Published in 2020 at "ACS Photonics"
DOI: 10.1021/acsphotonics.9b01317
Abstract: Single-molecule localization microscopy is a powerful technique with vast potential to study light-matter interactions at the nanoscale. Nanostructured environments can modify the fluorescence emission of single molecules and the induced decay-rate modification can be retrieved… read more here.
Keywords: fluorescence lifetime; single molecules; single molecule; microscopy ... See more keywords
Enhanced π-π Stacking between Dipole-Bearing Single Molecules Revealed by Conductance Measurement.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09656
Abstract: Dipoles are widely involved in π-π interactions and are central to many chemical and biological functions, but their influence on the strength of π-π interactions remains unclear. Here, we report a study of π-π interaction… read more here.
Keywords: single molecule; conductance; enhanced stacking; dipole ... See more keywords
Scale-Up of Room-Temperature Constructive Quantum Interference from Single Molecules to Self-Assembled Molecular-Electronic Films
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b13578
Abstract: The realization of self-assembled molecular-electronic films, whose room-temperature transport properties are controlled by quantum interference (QI), is an essential step in the scale-up of QI effects from single molecules to parallel arrays of molecules. Recently,… read more here.
Keywords: molecular electronic; single molecules; room temperature; self assembled ... See more keywords
Signals from single molecules
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Chemistry"
DOI: 10.1038/s41570-018-0045-3
Abstract: Following binding kinetics over time rather than relying on differences in free-energy of binding enables detection of single molecules of mutant DNA with an estimated specificity of 99.99999%. read more here.
Keywords: signals single; chemistry; single molecules;
Single molecules of terrylene in di-substituted naphthalenes crystallizing in the herringbone pattern
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c6ra27167g
Abstract: 2,3-Dichloronaphthalene (2,3-DCN) and 2,3-dibromonaphthalene (2,3-DBN) were synthesized, purified and used to grow single crystals in the form of thin plates. X-ray crystallographic studies, performed for the first time, showed that molecules in both isostructural crystals… read more here.
Keywords: herringbone pattern; molecules terrylene; terrylene substituted; single molecules ... See more keywords
Unraveling the impact of nano-scaling on silicon field-effect transistors for the detection of single-molecules.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr05267a
Abstract: Electrolyte-gated silicon field-effect transistors (FETs) capable of detecting single molecules could enable high-throughput molecular sensing chips to advance, for example, genomics or proteomics. For solid-gated silicon FETs it is well-known that nano-scaled devices become sensitive… read more here.
Keywords: field effect; effect transistors; nano scaling; silicon field ... See more keywords
Optical-nanofiber-based interface for single molecules
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review A"
DOI: 10.1103/physreva.97.043839
Abstract: Optical interfaces for quantum emitters are a prerequisite for implementing quantum networks. Here, we couple single molecules to the guided modes of an optical nanofiber. The molecules are embedded within a crystal that provides photostability… read more here.
Keywords: interface single; single molecules; optical nanofiber; based interface ... See more keywords
Single molecules can operate as primitive biological sensors, switches and oscillators
Sign Up to like & getrecommendations! Published in 2018 at "BMC Systems Biology"
DOI: 10.1186/s12918-018-0596-4
Abstract: BackgroundSwitch-like and oscillatory dynamical systems are widely observed in biology. We investigate the simplest biological switch that is composed of a single molecule that can be autocatalytically converted between two opposing activity forms. We test… read more here.
Keywords: molecule; single molecule; system; single molecules ... See more keywords