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   Articles with "single nephron" as a keyword



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Single-Nephron GFR in Patients With Obesity-Related Glomerulopathy

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recommendations! Published in 2020 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2020.05.013

Abstract: Introduction Obesity-related glomerulopathy (ORG) is a slowly progressive kidney disease occurring in association with obesity. It is characterized histopathologically by glomerulomegaly, likely caused by single-nephron hyperfiltration that has not been demonstrated in humans because of… read more here.

Keywords: single nephron; related glomerulopathy; obesity related; nephron ... See more keywords

Single-nephron proteomes connect morphology and function in proteinuric kidney disease.

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recommendations! Published in 2018 at "Kidney international"

DOI: 10.1016/j.kint.2017.12.012

Abstract: In diseases of many parenchymatous organs, heterogeneous deterioration of individual functional units determines the clinical prognosis. However, the molecular characterization at the level of such individual subunits remains a technological challenge that needs to be… read more here.

Keywords: kidney; single nephron; disease single; proteinuric kidney ... See more keywords

Development and validation of a single-nephron estimated glomerular filtration rate model to predict disease progression in IgA nephropathy

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recommendations! Published in 2025 at "BMC Nephrology"

DOI: 10.1186/s12882-025-04534-0

Abstract: The highly variable clinical progression of IgA nephropathy (IgAN) makes it challenging to accurately predict the risk of disease deterioration in patients. Although elevated single-nephron estimated glomerular filtration rate (eGFR) is implicated in disease progression,… read more here.

Keywords: egfr; disease; nephron; progression ... See more keywords

A new analysis approach for single nephron GFR in intravital microscopy of mice

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recommendations! Published in 2020 at "F1000Research"

DOI: 10.12688/f1000research.26888.3

Abstract: Background: Intravital microscopy is an emerging technique in life science with applications in kidney research. Longitudinal observation of (patho-)physiological processes in living mice is possible in the smallest functional unit of the kidney, a single… read more here.

Keywords: single nephron; microscopy; analysis; intravital microscopy ... See more keywords