Direct Readout of Single Nucleobase Variations in an Oligonucleotide.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201702011
Abstract: Direct, low-cost, label-free, and enzyme-free identification of single nucleobase is a great challenge for genomic studies. Here, this study reports that wild-type aerolysin can directly identify the difference of four types of single nucleobase (adenine,… read more here.
Keywords: dna; single nucleobase; nucleobase; direct readout ... See more keywords
Single nucleobase identification for transversally-confined ssDNA using longitudinal ionic currents.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr07116e
Abstract: High-fidelity DNA sequencing using solid-state nanopores remains a big challenge, partly due to difficulties related to efficient molecular capture and subsequent control of the dwell time. To help address these issues, here we propose a… read more here.
Keywords: dna; ssdna; nucleobase identification; longitudinal ionic ... See more keywords