A Single Radioprotective Dose of Prostaglandin E2 Blocks Irradiation-Induced Apoptotic Signaling and Early Cycling of Hematopoietic Stem Cells
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DOI: 10.1016/j.stemcr.2020.07.004
Abstract: Summary Ionizing radiation exposure results in acute and delayed bone marrow suppression. Treatment of mice with 16,16-dimethyl prostaglandin E2 (dmPGE2) prior to lethal ionizing radiation (IR) facilitates survival, but the cellular and molecular mechanisms are… read more here.
Keywords: prostaglandin; single radioprotective; stem cell; hematopoietic stem ... See more keywords